Evidence map›Paper›PMID 27003838›Full record

ArticleJournal of materials science. Materials in medicine2016

Surface morphology, tribological properties and in vitro biocompatibility of nanostructured zirconia thin films.

M Bianchi, A Gambardella, M Berni, S Panseri, M Montesi, N Lopomo, A Tampieri, M Marcacci, A Russo

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

M BianchiIstituto Ortopedico Rizzoli, Laboratorio di NanoBiotecnologie (NaBi), via di Barbiano 1/10, 40136, Bologna, Italy. michele.bianchi@ior.it.
A GambardellaIstituto Ortopedico Rizzoli, Laboratorio di NanoBiotecnologie (NaBi), via di Barbiano 1/10, 40136, Bologna, Italy.
M BerniIstituto Ortopedico Rizzoli, Laboratorio di NanoBiotecnologie (NaBi), via di Barbiano 1/10, 40136, Bologna, Italy.
S PanseriInstitute of Science and Technology for Ceramics, National Research Council of Italy, via Granarolo 64, 48018, Faenza, Italy.
M MontesiInstitute of Science and Technology for Ceramics, National Research Council of Italy, via Granarolo 64, 48018, Faenza, Italy.
N LopomoDipartimento di Ingegneria dell'Informazione, Università degli Studi di Brescia, via Branze 38, Brescia, Italy.
A TampieriInstitute of Science and Technology for Ceramics, National Research Council of Italy, via Granarolo 64, 48018, Faenza, Italy.
M MarcacciIstituto Ortopedico Rizzoli, Laboratorio di Biomeccanica e Innovazione Tecnologica, via di Barbiano 1/10, 40136, Bologna, Italy.
A RussoIstituto Ortopedico Rizzoli, Laboratorio di NanoBiotecnologie (NaBi), via di Barbiano 1/10, 40136, Bologna, Italy.
Istituto Ortopedico Rizzoli · ITNational Research Council · ITInstitute of Science and Technology for Ceramics · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deposition of nanostructured and low-wear zirconia (ZrO2) thin films on the metallic component of a total joint implant is envisaged to reduce wear of the soft ultra-high molecular weight polyethylene (UHMWPE) counterpart. In this work, morphological surface features, wear resistance and in vitro-biocompatibility of zirconia thin films deposited by the novel Pulsed Plasma Deposition (PPD) method have been investigated. Film thickness, roughness and wettability were found to be strongly dependent on deposition gas pressure. Interestingly, wear rate of UHMWPE disks coupled to zirconia-coated titanium spheres was only poorly correlated to the contact angle values, while film roughness and thickness seemed not to affect it. Furthermore, wear of UHMWPE, when coupled with zirconia coated-titanium spheres, significantly decreased with respect to uncoated spheres under dry or NaCl-lubricated conditions; besides, when using bovine serum, similar results were obtained for coated and uncoated spheres. Finally, suitable mesenchymal stem and osteoblast cells adhesion, proliferation and viability were observed, suggesting good biocompatibility of the nanostructured zirconia films. Taken together, the results shown in this work indicate that zirconia thin films deposited by the PPD method deserve further investigations as low-wear materials for biomedical applications such as total joint replacement.

Indexed as

Membranes, ArtificialAnimalsBiocompatible MaterialsCell ProliferationCell SurvivalMaterials TestingMesenchymal Stem CellsMiceNanostructuresSurface PropertiesZirconiumBiocompatible MaterialsMembranes, ArtificialZirconium

Identifiers

PMID27003838
OpenAlexW2309240829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.