Evidence map›Paper›PMID 27003496›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Frequent HIV Testing: Impact on HIV Risk Among Chinese Men Who Have Sex with Men.

Yu Liu, Han-Zhu Qian, Yuhua Ruan, Pingsheng Wu, Chandra Y Osborn, Yujiang Jia, Lu Yin, Hongyan Lu, Xiong He, Yiming Shao and 1 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  12. Self-Testing as a Hope to Reduce HIV in Transgender Women-Literature Review.International journal of environmental research and public health · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu Liu*Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN; †Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN; ‡State Key Laboratory of Infectious Disease Prevention and Control (SKLID), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China; §Departments of Biomedical Informatics; ‖Biostatistics, Vanderbilt University School of Medicine, Nashville, TN; ¶Division of General Internal Medicine and Public Health, Vanderbilt University School of Medicine, Nashville, TN; #Beijing Municipal Center for Disease Control and Prevention, Beijing, China; and **Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
Han-Zhu Qian
Yuhua Ruan
Pingsheng Wu
Chandra Y Osborn
Yujiang Jia
Lu Yin
Hongyan Lu
Xiong He
Yiming Shao
Sten H Vermund

Funding

Multi-component HIV Intervention Packages for Chinese MSMR01AI094562 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI QIAN, HAN-ZHU, VERMUND, STEN H. · 2011 to 2014
$2.5M
Expanded Testing, Linkage, and Treatment for HIV Prevention Among MSM in ChinaR34AI091446 · NIAID · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2011 to 2011
$226k
NIAID NIH HHS R01 AI094562NIAID NIH HHS R34 AI091446
6 · The paper itself

Abstract

backgroundThe HIV epidemic continues to expand among men who have sex with men (MSM) in China. The NIMH Project Accept/HPTN 043 trial suggested a borderline significant trend toward HIV incidence reduction among persons with higher testing rates.

methodsWe assessed HIV testing histories and infection status among a community-based Beijing MSM. HIV serostatus was lab confirmed. We ascertained demographic/behavioral factors through questionnaire-based interviews. Associations of previous HIV testing with odds of current HIV infection were assessed, seeking improved like-with-like risk comparisons through multivariable logistic regression analysis with propensity score adjustment and restricted cubic spline modeling.

resultsAmong 3588 participants, 12.7% were HIV infected; 70.8% reported having ever tested for HIV. Compared with MSM who never tested, those ever testing had a 41% reduction in the odds of being HIV positive [adjusted odds ratio (aOR): 0.59; 95% confidence interval (CI): 0.48 to 0.74. Higher HIV testing frequencies were associated with a decreasing trend in the odds of being infected with HIV vs. a referent group with no previous testing [>6 tests (aOR: 0.27; 95% CI: 0.18 to 0.41); 4-6 (aOR: 0.55; 95% CI: 0.39 to 0.78); 2-3 (aOR: 0.61; 95% CI: 0.45 to 0.82); P for trend <0.001]. The multivariable-adjusted model with restricted cubic spline of HIV testing frequency showed a higher frequency of previous HIV testing associated with lower odds of HIV infection, particularly among men with ≥10 lifetime male sexual partners.

conclusionsUsing risk probability adjustments to enable less biased comparisons, frequent HIV testing was associated with a lower HIV odds among Chinese MSM.

Indexed as

Mass ScreeningSexual BehaviorAdolescentAdultAgedChinaCross-Sectional StudiesHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleHumansIncidenceMaleMiddle AgedPropensity ScoreRisk Factors

Identifiers

PMID27003496
PMCPMC4925192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.