Evidence map›Paper›PMID 27002812›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2016

Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group.

Emerson M Wickwire, Scott G Williams, Thomas Roth, Vincent F Capaldi, Michael Jaffe, Margaret Moline, Gholam K Motamedi, Gregory W Morgan, Vincent Mysliwiec, Anne Germain and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 155 citations in OpenAlex.

  1. Guideline
  2. The Impact of Cognitive Behavioral Therapy for Insomnia on Neurofilament Light and Phosphorylated Tau in Individuals with a Concussion.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Trial
  3. Review
  4. Article
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  8. Review
  9. Article
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  19. Article
  20. Sleep Disturbances and Risk of Sports Injury Among Collegiate Student-Athletes.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2024
    Observational

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 1 country.

Emerson M WickwireDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA. ewickwire@medicine.umaryland.edu.
Scott G WilliamsDepartment of Medicine, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Thomas RothSleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI, USA.
Vincent F CapaldiDepartment of Behavioral Biology, Walter Reed Army Institute of Research, Center for Military Psychiatry and Neuroscience Research, Silver Spring, MD, USA.
Michael JaffeDepartment of Neurology, University of Florida, Gainesville, FL, USA.
Margaret MolineEisai, Inc., Woodcliff Lake, NJ, USA.
Gholam K MotamediDepartment of Neurology, Georgetown University Hospital, Washington, DC, USA.
Gregory W MorganSleep Disorders Center, National Intrepid Center of Excellence, Bethesda, MD, USA.
Vincent MysliwiecDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Anne GermainDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Renee M PazdanU.S. Public Health Service, Fort Carson, CO, USA.
Reuven FerzigerMerck and Co, Kenilworth, NJ, USA.
Thomas J BalkinDepartment of Behavioral Biology, Walter Reed Army Institute of Research, Center for Military Psychiatry and Neuroscience Research, Silver Spring, MD, USA.
Margaret E MacDonaldDefense and Veterans Brain Injury Center, (Contractor, General Dynamics Health Solutions), Evans Army Community Hospital, Fort Carson, CO, USA.
Thomas A MacekDepartment of Clinical Science, CNS, Takeda Development Center - Americas, Deerfield, IL, USA.
Michael R YochelsonMedstar National Rehabilitation Network, Washington, DC, USA.
Steven M ScharfSleep Disorders Center, Division of Pulmonary and Critical Care, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Christopher J LettieriDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Georgetown University · USUniformed Services University of the Health Sciences · USUniversity of Maryland, Baltimore · USWalter Reed Army Institute of Research · USDeerfield (United States) · USEisai (United States) · USEvans Army Community Hospital · USHenry Ford Hospital · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USUnited States Public Health Service · USUniversity of Florida Health · USUniversity of Pittsburgh · USWalter Reed National Military Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disturbed sleep is one of the most common complaints following traumatic brain injury (TBI) and worsens morbidity and long-term sequelae. Further, sleep and TBI share neurophysiologic underpinnings with direct relevance to recovery from TBI. As such, disturbed sleep and clinical sleep disorders represent modifiable treatment targets to improve outcomes in TBI. This paper presents key findings from a national working group on sleep and TBI, with a specific focus on the testing and development of sleep-related therapeutic interventions for mild TBI (mTBI). First, mTBI and sleep physiology are briefly reviewed. Next, essential empirical and clinical questions and knowledge gaps are addressed. Finally, actionable recommendations are offered to guide active and efficient collaboration between academic, industry, and governmental stakeholders.

Indexed as

ActigraphyAnimalsBrain ConcussionClinical Trials as TopicHumansPolysomnographySleepSleep Wake DisordersConcussionInsomniaSleepSleep apneaSleep disordersTraumatic brain injury

Identifiers

PMID27002812
PMCPMC4824019
OpenAlexW2306237590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.