ReviewInternal and emergency medicine2016
Cardiovascular disease and hypertension in sub-Saharan Africa: burden, risk and interventions.
Review in Internal and emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
135 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Risk factors for cardiovascular diseases in patients with vitiligo: an analysis of current evidence.Annals of medicine · 2024Pooled it
- Projected burden and distribution of elevated blood pressure levels and its consequence among adolescents in sub-Saharan Africa.Journal of global health · 2024Pooled it
- Pooled it
- A systematic review and meta-analysis of cardiovascular diseases and associated factors among diabetes mellitus patients in Ethiopia.BMC cardiovascular disorders · 2023Pooled it
- Different Doses of Sacubitril/Valsartan Compared with Olmesartan in Patients with Essential Hypertension: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Pooled it
- Healthcare professionals' level of medication knowledge in Africa: a systematic review.British journal of clinical pharmacology · 2018Pooled it
- Pooled it
- Self-Care for the Prevention and Management of Cardiovascular Disease and Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association.Journal of the American Heart Association · 2017Guideline
- Biophotonics point-of-care diagnostics in low-resource settings: a South African perspective.Journal of biomedical optics · 2026Review
- Multilevel analysis of noncommunicable diseases and associated factors among Ethiopian adults: evidence from the 2024 STEPS survey.Tropical medicine and health · 2026Article
- Review
- Epigenome-wide analysis in West Africans identifies DNA methylation markers for circulating adiponectin.EBioMedicine · 2026Article
- Assessment of Hospital Overcrowding Perceptions and Outpatient Care Quality Among Hypertensive Patients in Mampong, Ghana: A Cross-Sectional Study.Health science reports · 2026Article
- The Urgent Need to Harness Public Health Interventions to Tackle the Burden of Cardiovascular Diseases in Africa: Opportunities, Challenges, and Recommendations.Health science reports · 2026Article
- Comparative efficacy and safety of chlorthalidoneWorld journal of cardiology · 2026Article
- Barriers to Blood Pressure Control in Treated Patients Attending Public Primary Healthcare Clinics in Gaborone, Botswana.Public health challenges · 2025Article
- Narrative review of mitochondrial dysfunction in aging-related salt-sensitive hypertension: outcomes, mechanisms, and therapeutic implications.Aging advances · 2025Article
- Prevalence, Determinants, and Time Trends of Cardiovascular Health in the WHO African Region.JAMA cardiology · 2025Article
- Article
- Prevalence and determinants of hypertension in rwanda: a secondary data analysis using the WHO STEPS survey 2022.Scientific reports · 2025Article
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease, including stroke, heart failure and kidney disease, has been common in sub-Saharan Africa for many years, and rapid urbanization is causing an upsurge of ischaemic heart disease and metabolic disorders. At least two-thirds of cardiovascular deaths now occur in low- and middle-income countries, bringing a double burden of disease to poor and developing world economies. High blood pressure (or hypertension) is by far the commonest underlying risk factor for cardiovascular disease. Its prevention, detection, treatment and control in sub-Saharan Africa are haphazard and suboptimal. This is due to a combination of lack of resources and health-care systems, non-existent effective preventive strategies at a population level, lack of sustainable drug therapy, and barriers to complete compliance with prescribed medications. The economic impact for loss of productive years of life and the need to divert scarce resources to tertiary care are substantial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.