ArticleProceedings of the National Academy of Sciences of the United States of America2016
Direction of information flow in large-scale resting-state networks is frequency-dependent.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 1 of them a synthesis that pooled it.
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Who cites it
193 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of MEG-based studies in Parkinson's disease: The motor system and beyond.Human brain mapping · 2019Pooled it
- Comparative efficacy of dual- vs. single-node tACS in amnestic mild cognitive impairment: behavioral and EEG evidence.Translational psychiatry · 2026Trial
- Medial parietal alpha-frequency transcranial alternating current stimulation for chronic insomnia: a randomized sham-controlled trial.Psychological medicine · 2025Trial
- Advances in causal discovery methods for ecological time series.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Frequency-Specific Neural Dynamics and Decoding of Hierarchical Auditory Sequences Revealed by Magnetoencephalography.Neuroscience bulletin · 2026Article
- Sub-second fluctuations between top-down and bottom-up modes distinguish diverse human brain states.Current biology : CB · 2026Article
- Different modulation patterns of theta and gamma dual-site HD-tACS on cognitive impairment.iScience · 2026Article
- Neural Oscillations Supporting Gender Categorization of Faces and Body Silhouettes.Annals of the New York Academy of Sciences · 2026Article
- Distinct Resting-State Connectomes for Face and Scene Perception Predict Individual Task Performance.Human brain mapping · 2026Article
- The role of white matter myelin in structural-functional network coupling.Communications biology · 2026Article
- Directed cortico-limbic dialogue in the human brain.Nature communications · 2026Article
- Linking EEG markers of oscillopathy and default mode network dysfunction in Alzheimer's disease.Frontiers in human neuroscience · 2026Review
- Oscillatory dynamics as the coordination layer of the organism: waves, Markov blankets, and the virtual space of cognition.Frontiers in neuroscience · 2026Article
- Evaluating oscillatory mechanisms underlying flexible neural communication in the human brain.Network neuroscience (Cambridge, Mass.) · 2026Article
- Simultaneous tDCS-rTMS stimulation to regulate the language network and improve language ability in Landau-Kleffner syndrome.Epilepsia open · 2025Article
- Evaluating oscillatory mechanisms underlying flexible neural communication in the human brain.bioRxiv : the preprint server for biology · 2025Article
- EEG Biomarkers for a Precision-Medicine Approach to Noninvasive Brain Stimulation for Major Depressive Disorder.Research square · 2025Article
- Large-scale cortical functional networks are organized in structured cycles.Nature neuroscience · 2025Article
- Alpha oscillations mediate inhibitory control and perceptual transitions during binocular rivalry.iScience · 2025Article
- COMPLEX-VALUED PHASE SYNCHRONY REVEALS DIRECTIONAL COUPLING IN FMRI AND TRACKS MEDICATION EFFECTS.ArXiv · 2025Article
133 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Normal brain function requires interactions between spatially separated, and functionally specialized, macroscopic regions, yet the directionality of these interactions in large-scale functional networks is unknown. Magnetoencephalography was used to determine the directionality of these interactions, where directionality was inferred from time series of beamformer-reconstructed estimates of neuronal activation, using a recently proposed measure of phase transfer entropy. We observed well-organized posterior-to-anterior patterns of information flow in the higher-frequency bands (alpha1, alpha2, and beta band), dominated by regions in the visual cortex and posterior default mode network. Opposite patterns of anterior-to-posterior flow were found in the theta band, involving mainly regions in the frontal lobe that were sending information to a more distributed network. Many strong information senders in the theta band were also frequent receivers in the alpha2 band, and vice versa. Our results provide evidence that large-scale resting-state patterns of information flow in the human brain form frequency-dependent reentry loops that are dominated by flow from parieto-occipital cortex to integrative frontal areas in the higher-frequency bands, which is mirrored by a theta band anterior-to-posterior flow.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.