ArticleThe American journal of tropical medicine and hygiene2016
Investigation of Recurrent Melioidosis in Lao People's Democratic Republic by Multilocus Sequence Typing.
Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Case Report: Genetic evolution ofWellcome open research · 2025Article
- A systematic review and meta-analysis of the global prevalence and relationships amongVeterinary world · 2024Article
- Phenotypic and genetic alterations ofFrontiers in microbiology · 2023Article
- The Epidemiology of Melioidosis and Its Association with Diabetes Mellitus: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2022Article
- Human Melioidosis.Clinical microbiology reviews · 2020Review
- Melioidosis: The hazards of incomplete peer-review.PLoS neglected tropical diseases · 2019Article
- Evaluation of a Rapid Diagnostic Test for Detection of Burkholderia pseudomallei in the Lao People's Democratic Republic.Journal of clinical microbiology · 2018Article
- Melioidosis.Nature reviews. Disease primers · 2018Review
- Observational
- Utility of a Lateral Flow Immunoassay (LFI) to Detect Burkholderia pseudomallei in Soil Samples.PLoS neglected tropical diseases · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Melioidosis is an infectious disease caused by the saprophytic bacterium Burkholderia pseudomallei In northeast Thailand and northern Australia, where the disease is highly endemic, a range of molecular tools have been used to study its epidemiology and pathogenesis. In the Lao People's Democratic Republic (Laos) where melioidosis has been recognized as endemic since 1999, no such studies have been undertaken. We used a multilocus sequence typing scheme specific for B. pseudomallei to investigate nine cases of culture-positive recurrence occurring in 514 patients with melioidosis between 2010 and 2015: four were suspected to be relapses while the other five represented reinfections. In addition, two novel sequence types of the bacterium were identified. The low overall recurrence rates (2.4%) and proportions of relapse and reinfection in the Laos are consistent with those described in the recent literature, reflecting the effective use of appropriate antimicrobial therapy.
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