Evidence map›Paper›PMID 27001735›Full record

ArticleNature chemistry2016

Chemical amplification of magnetic field effects relevant to avian magnetoreception.

Daniel R Kattnig, Emrys W Evans, Victoire Déjean, Charlotte A Dodson, Mark I Wallace, Stuart R Mackenzie, Christiane R Timmel, P J Hore

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
21.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 117 citations in OpenAlex.

  1. Article
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  4. Spin-Dependent Photoluminescence in Carbon-Based Quantum Dots.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  5. A hybrid compass mechanism combining radical pairs and magnetite crystals.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Daniel R KattnigDepartment of Chemistry, University of Oxford, Physical &Theoretical Chemistry Laboratory, Oxford OX1 3QZ, UK.
Emrys W EvansDepartment of Chemistry, University of Oxford, Inorganic Chemistry Laboratory, Oxford OX1 3QR, UK.
Victoire DéjeanDepartment of Chemistry, University of Oxford, Inorganic Chemistry Laboratory, Oxford OX1 3QR, UK.
Charlotte A DodsonDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, UK.
Mark I WallaceDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, UK.
Stuart R MackenzieDepartment of Chemistry, University of Oxford, Physical &Theoretical Chemistry Laboratory, Oxford OX1 3QZ, UK.
Christiane R TimmelDepartment of Chemistry, University of Oxford, Inorganic Chemistry Laboratory, Oxford OX1 3QR, UK.
P J HoreDepartment of Chemistry, University of Oxford, Physical &Theoretical Chemistry Laboratory, Oxford OX1 3QZ, UK.
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic fields as weak as the Earth's can change the yields of radical pair reactions even though the energies involved are orders of magnitude smaller than the thermal energy, kBT, at room temperature. Proposed as the source of the light-dependent magnetic compass in migratory birds, the radical pair mechanism is thought to operate in cryptochrome flavoproteins in the retina. Here we demonstrate that the primary magnetic field effect on flavin photoreactions can be amplified chemically by slow radical termination reactions under conditions of continuous photoexcitation. The nature and origin of the amplification are revealed by studies of the intermolecular flavin-tryptophan and flavin-ascorbic acid photocycles and the closely related intramolecular flavin-tryptophan radical pair in cryptochrome. Amplification factors of up to 5.6 were observed for magnetic fields weaker than 1 mT. Substantial chemical amplification could have a significant impact on the viability of a cryptochrome-based magnetic compass sensor.

Indexed as

Magnetic FieldsAnimalsAscorbic AcidCryptochromesFlavinsLightMuramidaseSensory Receptor CellsTryptophanAscorbic AcidCryptochromesFlavinsMuramidaseTryptophan

Identifiers

PMID27001735
OpenAlexW2264376628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.