ArticleNucleic acids research2016
Inducible DamID systems for genomic mapping of chromatin proteins in Drosophila.
Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 52 citations in OpenAlex.
- Article
- Binding of Transcriptional Activator to Silent Loci Causes Their Detachment from the Nuclear Lamina inInternational journal of molecular sciences · 2025Article
- Epigenetic Regulation in Drosophila Tumor Models.Advances in experimental medicine and biology · 2025Review
- PIGB maintains nuclear lamina organization in skeletal muscle of Drosophila.The Journal of cell biology · 2024Article
- Article
- Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC.BMC genomics · 2023Article
- Long range inter-chromosomal interaction of Oct4 distal enhancer loci regulates ESCs pluripotency.Cell death discovery · 2023Article
- DamID-seq: A Genome-Wide DNA Methylation Method that Captures Both Transient and Stable TF-DNA Interactions in Plant Cells.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Comparison of genome architecture at two stages of male germline cell differentiation in Drosophila.Nucleic acids research · 2022Article
- Targeted DamID inScience advances · 2022Article
- Gene expression profiling of epidermal cell types in C. elegans using Targeted DamID.Development (Cambridge, England) · 2021Article
- Article
- Various modes of HP1a interactions with the euchromatic chromosome arms in Drosophila ovarian somatic cells.Chromosoma · 2020Article
- Cell cycle dynamics of lamina-associated DNA.EMBO reports · 2020Article
- Recent advances in the spatial organization of the mammalian genome.Journal of biosciences · 2020Review
- The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine.Nature communications · 2019Article
- Dam mutants provide improved sensitivity and spatial resolution for profiling transcription factor binding.Epigenetics & chromatin · 2019Article
- DamID as a versatile tool for understanding gene regulation.Development (Cambridge, England) · 2019Review
- Review
- New slbo-Gal4 driver lines for the analysis of border cell migration during Drosophila oogenesis.Chromosoma · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Dam identification (DamID) is a powerful technique to generate genome-wide maps of chromatin protein binding. Due to its high sensitivity, it is particularly suited to study the genome interactions of chromatin proteins in small tissue samples in model organisms such as Drosophila Here, we report an intein-based approach to tune the expression level of Dam and Dam-fusion proteins in Drosophila by addition of a ligand to fly food. This helps to suppress possible toxic effects of Dam. In addition, we describe a strategy for genetically controlled expression of Dam in a specific cell type in complex tissues. We demonstrate the utility of the latter by generating a glia-specific map of Polycomb in small samples of brain tissue. These new DamID tools will be valuable for the mapping of binding patterns of chromatin proteins in Drosophila tissues and especially in cell lineages.
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Registered trials
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