ArticleScientific reports2016
Functional Connectome before and following Temporal Lobectomy in Mesial Temporal Lobe Epilepsy.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Contralateral language network integration predicts and protects against naming decline after temporal lobe resection.Epilepsia · 2026Article
- Thalamic organization differentially contributes to clinical conditions in epilepsy.Communications medicine · 2026Article
- Multi-modal connectome analysis of the stereoelectroencephalography implantation effect: a case report.Clinical neurophysiology practice · 2026Article
- The impact of resective epilepsy surgery on the brain network: evidence from post-surgical imaging.Brain : a journal of neurology · 2025Review
- Change in Structural Connectivity Following Stereotactic Thermocoagulation in Mesial Temporal Lobe Epilepsy Patients.European journal of neurology · 2025Article
- Independent component analysis of resting-state fMRI identifies regions associated with seizure freedom after laser interstitial thermal therapy for temporal lobe epilepsy.Frontiers in neurology · 2025Article
- Association Between Postsurgical Functional Connectivity and Seizure Outcome in Patients With Temporal Lobe Epilepsy.Neurology · 2024Article
- Individual cerebellar metabolic connectome in patients with MTLE and NTLE associated with surgical prognosis.European journal of nuclear medicine and molecular imaging · 2024Article
- Predictors of long-term memory and network connectivity 10 years after anterior temporal lobe resection.Epilepsia · 2024Article
- Article
- Recent Advances in Neuroimaging of Epilepsy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
- Large-scale resculpting of cortical circuits in children after surgical resection.Scientific reports · 2020Article
- Identification of neural networks preferentially engaged by epileptogenic mass lesions through lesion network mapping analysis.Scientific reports · 2020Article
- Brainstem Functional Connectivity Disturbances in Epilepsy may Recover After Successful Surgery.Neurosurgery · 2020Article
- Post-traumatic Stress Disorder With Flashbacks of an Old Childhood Memory Triggered by Right Temporal Lobe Epilepsy Surgery in Adulthood.Frontiers in psychiatry · 2020Article
- Lesion Network Localization of Seizure Freedom following MR-guided Laser Interstitial Thermal Ablation.Scientific reports · 2019Article
- Article
- Characterization of brain network supporting episodic memory in the absence of one medial temporal lobe.Human brain mapping · 2019Article
- The impact of epilepsy surgery on the structural connectome and its relation to outcome.NeuroImage. Clinical · 2018Article
- Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy.NeuroImage. Clinical · 2018Article
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 2 countries.
Funding
Abstract
As mesial temporal lobe epilepsy (mTLE) has been recognized as a network disorder, a longitudinal connectome investigation may shed new light on the understanding of the underlying pathophysiology related to distinct surgical outcomes. Resting-state functional MRI data was acquired from mTLE patients before (n = 37) and after (n = 24) anterior temporal lobectomy. According to surgical outcome, patients were classified as seizure-free (SF, n = 14) or non-seizure-free (NSF, n = 10). First, we found higher network resilience to targeted attack on topologically central nodes in the SF group compared to the NSF group, preoperatively. Next, a two-way mixed analysis of variance with between-subject factor 'outcome' (SF vs. NSF) and within-subject factor 'treatment' (pre-operation vs. post-operation) revealed divergent dynamic reorganization in nodal topological characteristics between groups, in the temporoparietal junction and its connection with the ventral prefrontal cortex. We also correlated the network damage score (caused by surgical resection) with postsurgical brain function, and found that the damage score negatively correlated with postoperative global and local parallel information processing. Taken together, dynamic connectomic architecture provides vital information for selecting surgical candidates and for understanding brain recovery mechanisms following epilepsy surgery.
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