Observational studyPediatric nephrology (Berlin, Germany)2016
Incidence of contrast-induced acute kidney injury in a pediatric setting: a cohort study.
Observational study in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- FermentedRenal failure · 2024Pooled it
- State-of-the-Art Renal Imaging in Children.Pediatrics · 2020Pooled it
- Mechanical Thrombectomy for Pediatric Acute Ischemic Stroke With Large Vessel Occlusion: Technical Guide and Case Series.Stroke (Hoboken, N.J.) · 2026Article
- Contrast-induced acute kidney injury and nephrogenic systemic fibrosis in children.Pediatric nephrology (Berlin, Germany) · 2026Review
- LncRNA HILPDA promotes contrast-induced acute kidney injury by recruiting eIF4B to upregulate XPO1 expression.Toxicology research · 2024Article
- Low-iodine-dose computed tomography coupled with an artificial intelligence-based contrast-boosting technique in children: a retrospective study on comparison with conventional-iodine-dose computed tomography.Pediatric radiology · 2024Article
- Risk of acute kidney injury following contrast-enhanced CT or MRI in a cohort of 3061 hospitalized children in China.BMC pediatrics · 2024Article
- PICS/AEPC/APPCS/CSANZ/SCAI/SOLACI: Expert Consensus Statement on Cardiac Catheterization for Pediatric Patients and Adults With Congenital Heart Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Should the Radiologist Always Request a Blood Test Before an Emergency CT Scan in Children.Journal of the Belgian Society of Radiology · 2024Article
- Safety considerations related to intravenous contrast agents in pediatric imaging.Pediatric radiology · 2023Review
- Contrast-Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy in A Neonate with Aortic Stenosis-A Case Report.Pediatric reports · 2023Article
- Burden and Risk Factors of Contrast-Associated Acute Kidney Injury in Hospitalized Zambian Children: A Prospective Cohort Study at the University Teaching Hospitals.Canadian journal of kidney health and disease · 2023Article
- Quercetin improves contrast-induced acute kidney injury through the HIF-1α/lncRNA NEAT1/HMGB1 pathway.Pharmaceutical biology · 2022Article
- Contrast-enhanced ultrasound is useful for the evaluation of focal liver lesions in children.Australasian journal of ultrasound in medicine · 2021Article
- Incidence, Risk Factors, the Role of Plasma NGAL and Outcome of Contrast-Induced Acute Kidney Injury in Critically Ill Children.Indian journal of pediatrics · 2021Article
- Chest CTA in children younger than two years - a retrospective comparison of three contrast injection protocols.Scientific reports · 2019Article
- Practical administration of intravenous contrast media in children: screening, prophylaxis, administration and treatment of adverse reactions.Pediatric radiology · 2019Review
- Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines.European radiology · 2018Review
- Understanding and preventing contrast-induced acute kidney injury.Nature reviews. Nephrology · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContrast-induced acute kidney injury (CI-AKI) is a common pathology among adult patients, with an incidence ranging from 3-25 % depending on risk factors. Little information is available regarding CI-AKI incidence, risk factors, and prognostic impact in the pediatric population.
methodsWe performed a retrospective study of pediatric patients who underwent computed tomography (CT) scan with iodinated contrast media injection between 2005 and 2014 in five pediatric units of a university hospital. CI-AKI was defined according to Kidney Disease/Improving Global Outcomes (KDIGO) criteria.
resultsOf 346 identified patients, 233 had renal function follow-up and were included in our analyses. CI-AKI incidence was 10.3 % [95 % confidence interval (CI) 6.4-14.2 %]. CI-AKI was associated with 30-day unfavorable outcome before (45.8 % vs. 19.7 %, P = 0.007) and after [odds ratio (OR) 3.6; 95 % CI 1.4-9.5] adjustment for confounders. No independent risk factors of CI-AKI were identified.
conclusionsCI-AKI incidence was as high as 10.3 % following intravenous contrast media administration in the pediatric setting. As reported among adults, CI-AKI was associated with unfavorable outcome after adjustment for confounders. Although additional studies are needed in the pediatric setting, our data suggest that physicians should maintain a high degree of suspicion toward this complication among pediatric patients.
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