Evidence map›Paper›PMID 27000446›Full record

Trial reportJournal of neuroengineering and rehabilitation2016

Sequencing bilateral robot-assisted arm therapy and constraint-induced therapy improves reach to press and trunk kinematics in patients with stroke.

Yu-wei Hsieh, Rong-jiuan Liing, Keh-chung Lin, Ching-yi Wu, Tsan-hon Liou, Jui-chi Lin, Jen-wen Hung

2 registry-linked trialsAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01727648 naunknown statusnot on this map

Effects of Robot-Assisted Therapy in Sequential Combination With Constraint-Induced Therapy in Stroke Rehabilitation

TypeinterventionalSponsorNational Taiwan University HospitalRan2012 to 2015Enrolled92ConditionsCerebrovascular AccidentArmsRT in sequential combination with dCIT, Distributed Constraint-Induced Therapy, Robot-Assisted Therapy, Dose-matched control therapy
NCT05683158 completednot on this mapstarted 2022, after this paper: background citation

Compensatory Kinematic Movement for Reaching Task in Various Directions in After Stroke

TypeobservationalSponsorUniversity of ValenciaRan2022 to 2023Enrolled96ConditionsCerebral Stroke, Hemiplegia, Spastic
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-wei HsiehDepartment of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, and Healthy Aging Research Center, Chang Gung University, 259 Wenhua 1st Rd, Taoyuan, Taiwan.
Rong-jiuan LiingSchool of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Keh-chung LinSchool of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ching-yi WuDepartment of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, and Healthy Aging Research Center, Chang Gung University, 259 Wenhua 1st Rd, Taoyuan, Taiwan. cywu@mail.cgu.edu.tw.ORCID http://orcid.org/0000-0003-4726-2916
Tsan-hon LiouDepartment of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.
Jui-chi LinDepartment of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.
Jen-wen HungDepartment of Rehabilitation, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combination of robot-assisted therapy (RT) and a modified form of constraint-induced therapy (mCIT) shows promise for improving motor function of patients with stroke. However, whether the changes of motor control strategies are concomitant with the improvements in motor function after combination of RT and mCIT (RT + mCIT) is unclear. This study investigated the effects of the sequential combination of RT + mCIT compared with RT alone on the strategies of motor control measured by kinematic analysis and on motor function and daily performance measured by clinical scales.

methodsThe study enrolled 34 patients with chronic stroke. The data were derived from part of a single-blinded randomized controlled trial. Participants in the RT + mCIT and RT groups received 20 therapy sessions (90 to 105 min/day, 5 days for 4 weeks). Patients in the RT + mCIT group received 10 RT sessions for first 2 weeks and 10 mCIT sessions for the next 2 weeks. The Bi-Manu-Track was used in RT sessions to provide bilateral practice of wrist and forearm movements. The primary outcome was kinematic variables in a task of reaching to press a desk bell. Secondary outcomes included scores on the Wolf Motor Function Test, Functional Independence Measure, and Nottingham Extended Activities of Daily Living. All outcome measures were administered before and after intervention.

resultsRT + mCIT and RT demonstrated different benefits on motor control strategies. RT + mCIT uniquely improved motor control strategies by reducing shoulder abduction, increasing elbow extension, and decreasing trunk compensatory movement during the reaching task. Motor function and quality of the affected limb was improved, and patients achieved greater independence in instrumental activities of daily living. Force generation at movement initiation was improved in the patients who received RT.

conclusionA combination of RT and mCIT could be an effective approach to improve stroke rehabilitation outcomes, achieving better motor control strategies, motor function, and functional independence of instrumental activities of daily living.

trial registrationClinicalTrials.gov. NCT01727648.

Indexed as

Stroke RehabilitationActivities of Daily LivingAgedBiomechanical PhenomenaCombined Modality TherapyExercise TherapyFemaleHumansMaleMiddle AgedMovementRoboticsTreatment OutcomeConstraint-inducedRobotic rehabilitationSequential combination therapyStrokeUpper extremity

Identifiers

PMID27000446
PMCPMC4802889

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.