Evidence map›Paper›PMID 27000405›Full record

Observational studyReproductive health2016

Prevalence of depressive symptoms in pregnant and postnatal HIV-positive women in Ukraine: a cross-sectional survey.

Heather Bailey, Ruslan Malyuta, Igor Semenenko, Claire L Townsend, Mario Cortina-Borja, Claire Thorne, Ukraine European Collaborative Study in EuroCoord

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Reproductive health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Anxiety and Depression Among Women Living with HIV: Prevalence and Correlations.Clinical practice and epidemiology in mental health : CP & EMH · 2020
    Article
  8. Article
  9. Depression and HIV Disease Progression: A Mini-Review.Clinical practice and epidemiology in mental health : CP & EMH · 2019
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Heather BaileyPopulation, Policy and Practice Programme, UCL Institute of Child Health, University College London, London, UK. heather.bailey@ucl.ac.uk.
Ruslan MalyutaPerinatal Prevention of AIDS Initiative, Odessa, Ukraine.
Igor SemenenkoPerinatal Prevention of AIDS Initiative, Odessa, Ukraine.
Claire L TownsendUCL Institute of Child Health, University College London, London, UK.
Mario Cortina-BorjaUCL Institute of Child Health, University College London, London, UK.
Claire ThorneUCL Institute of Child Health, University College London, London, UK.
Ukraine European Collaborative Study in EuroCoord

Funding

RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
Department of HealthMedical Research Council G0400546NIMHD NIH HHS U54 MD007584Wellcome TrustWellcome Trust 081082
6 · The paper itself

Abstract

backgroundPerinatal depression among HIV-positive women has negative implications for HIV-related and other maternal and infant outcomes. The aim of this study was to investigate the burden and correlates of perinatal depression among HIV-positive women in Ukraine, a lower middle income country with one of the largest HIV-positive populations in Europe.

methodsCross-sectional surveys nested within the Ukraine European Collaborative Study were conducted of HIV-positive women at delivery and between 1 and 12 months postpartum. Depressive symptoms in the previous month were assessed using a self-report screening tool. Other data collected included demographics, antiretroviral therapy (ART)-related self-efficacy, and perceptions of risks/benefits of interventions to prevent mother-to-child transmission (PMTCT). Characteristics of women with and without a positive depression screening test result were compared using Fisher's exact test and χ2 test for categorical variables.

resultsA quarter (27% (49/180) antenatally and 25% (57/228) postnatally) of participants screened positive for depressive symptoms. Antenatal risk factors were living alone (58% (7/12) vs. 25% (42/167) p = 0.02), being somewhat/terribly bothered by ART side effects (40% (17/43) vs. 23% (30/129) not /only slightly bothered, p = 0.05) and having lower ART-related self-efficacy (43% (12/28) vs. 23% (25/110) with higher self-efficacy, p = 0.05). Postnatally, single mothers were more likely to screen positive (44% (20/45) vs. 21% (18/84) of cohabiting and 19% (19/99) of married women, p < 0.01) as were those unsure of the effectiveness of neonatal prophylaxis (40% (20/45) vs. 18% (28/154) sure of effectiveness, p < 0.01), those worried that neonatal prophylaxis could harm the baby (30% (44/146) vs. 14% (10/73) not worried p < 0.01) and those not confident to ask for help with taking ART (48% (11/23) vs. 27% (10/37) fairly confident and 15 % (4/26) confident that they could do this). Of women who reported wanting help for their depressive symptoms, 82% (37/45) postnatally but only 31% (12/39) antenatally were already accessing peer counselling, treatment adherence programmes, support groups or social services.

conclusionsA quarter of women screened positive for depression. Results highlight the need for proactive strategies to identify depressive symptoms, and an unmet need for provision of mental health support in the perinatal period for HIV-positive women in Ukraine.

Indexed as

AdultAnti-Retroviral AgentsCohort StudiesCost of IllnessCross-Sectional StudiesDepressionDepression, PostpartumFemaleHealth SurveysHIV SeropositivityHumansLost to Follow-UpMass ScreeningPatient Acceptance of Health CarePostpartum PeriodPregnancyAnti-Retroviral AgentsAntiretroviral therapyDepressionEastern EuropeHIV infectionPostpartum periodPregnancyPrevention of mother-to-child transmissionUkraine

Identifiers

PMID27000405
PMCPMC4802605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.