Trial reportJournal of the American Geriatrics Society2016
Multifaceted Prospective Memory Intervention to Improve Medication Adherence.
Trial report in Journal of the American Geriatrics Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Protocol of a Feasibility Randomized Controlled Trial
Digital Technology to Support Adherence to Hypertension Medications for Older Adults With Mild Cognitive Impairment
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prospective Memory Training in Older Adults: A Systematic Review and Meta-Analysis.Neuropsychology review · 2023Pooled it
- Interventions for improving medication-taking ability and adherence in older adults prescribed multiple medications.The Cochrane database of systematic reviews · 2020Pooled it
- Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial.JMIR mHealth and uHealth · 2020Trial
- [Developmental trajectories of medication adherence and predictors of latent classes in patients with ischemic stroke].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Compensatory Strategies to Improve Functional Cognition Post-Stroke: A Review for Caregiver Empowerment and Burden Reduction.Brain sciences · 2025Review
- Electronic Monitoring of Medication Adherence to Direct Oral Anticoagulants: A Systematic Review.Patient preference and adherence · 2025Review
- Developing decision support algorithm for hypertension medications for use in a digital therapeutic system.Frontiers in drug safety and regulation · 2025Article
- Mobility-Based Smartphone Digital Phenotypes for Unobtrusively Capturing Everyday Cognition, Mood, and Community Life-Space in Older Adults: Feasibility, Acceptability, and Preliminary Validity Study.JMIR human factors · 2024Article
- Developing feedback visualizations to support older adults' medication adherence.Human factors in healthcare · 2024Article
- Translation of a Successful Behavioral Intervention to a Digital Therapeutic Self-Management System for Older Adults.Ergonomics in design : the magazine of human factors applications · 2024Article
- A rapid review of interventions to improve medicine self-management for older people living at home.Health expectations : an international journal of public participation in health care and health policy · 2023Review
- Designing Feedback Visualizations for Anti-Hypertensive Medication Adherence for Older Adults.Proceedings of the Human Factors and Ergonomics Society ... Annual Meeting. Human Factors and Ergonomics Society. Annual meeting · 2022Article
- A Participatory Sensing Study to Understand the Problems Older Adults Faced in Developing Medication-Taking Habits.Healthcare (Basel, Switzerland) · 2022Article
- Enhancing cue salience improves aspects of naturalistic time-based prospective memory in older adults with HIV disease.Neuropsychology · 2021Article
- Home Care Patients' Experiences with Home Care Nurses' Support in Medication Adherence.Patient preference and adherence · 2021Article
- A Pantheoretical Framework to Optimize Adherence to Healthy Lifestyle Behaviors and Medication Adherence: The Use of Personalized Approaches to Overcome Barriers and Optimize Facilitators to Achieve Adherence.JMIR mHealth and uHealth · 2020Article
- Impact of multimodal interventions on medication nonadherence among elderly hypertensives: a randomized controlled study.Patient preference and adherence · 2019Article
- User Insights for Design of an Antihypertensive Medication Management Application.Proceedings of the Human Factors and Ergonomics Society ... Annual Meeting. Human Factors and Ergonomics Society. Annual meeting · 2018Article
- Neurocognitive Function in Children with Primary Hypertension after Initiation of Antihypertensive Therapy.The Journal of pediatrics · 2018Observational
- Using Smart City Technology to Make Healthcare Smarter.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo test whether a multifaceted prospective memory intervention improved adherence to antihypertensive medications and to assess whether executive function and working memory processes moderated the intervention effects.
designTwo-group longitudinal randomized control trial.
settingCommunity.
participantsIndividuals aged 65 and older without signs of dementia or symptoms of severe depression who were self-managing prescribed medication. MEASUREMENTS: After 4 weeks of initial adherence monitoring using a medication event monitoring system, individuals with 90% or less adherence were randomly assigned to groups.
interventionThe prospective memory intervention was designed to provide strategies that switch older adults from relying on executive function and working memory processes (that show effects of cognitive aging) to mostly automatic associative processes (that are relatively spared with normal aging) for remembering to take medications. Strategies included establishing a routine, establishing cues strongly associated with medication taking actions, performing the action immediately upon thinking about it, using a medication organizer, and imagining medication taking to enhance encoding and improve cuing.
resultsThere was significant improvement in adherence in the intervention group (57% at baseline to 78% after the intervention), but most of these gains were lost after 5 months. The control condition started at 68% and was stable during the intervention, but dropped to 62%. Executive function and working memory moderated the intervention effect, with the intervention producing greater benefit for those with lower executive function and working memory.
conclusionThe intervention improved adherence, but the benefits were not sustained. Further research is needed to determine how to sustain the substantial initial benefits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.