Trial reportJournal of the American Geriatrics Society2016
Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations.
Trial report in Journal of the American Geriatrics Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections.The Cochrane database of systematic reviews · 2020Pooled it
- Trial
- Associations of spirometricFrontiers in public health · 2026Article
- Chronic Obstructive Pulmonary Disease: Lifestyle Impact.International journal of preventive medicine · 2024Review
- Influence of Walking as Physiological Training to Improve Respiratory Parameters in the Elderly Population.International journal of environmental research and public health · 2022Review
- The association of walking pace and incident heart failure and subtypes among postmenopausal women.Journal of the American Geriatrics Society · 2022Article
- Dyspnea is associated with poor physical performance among community-dwelling older adults: a population-based cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2020Article
- Lifestyle interventions in prevention and comprehensive management of COPD.Breathe (Sheffield, England) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate the effect of structured physical activity on respiratory outcomes in community-dwelling elderly adults with mobility limitations.
designMulticenter, randomized trial of physical activity vs health education, with respiratory variables prespecified as tertiary outcomes over an intervention period of 24-42 months. Physical activity included walking (goal of 150 min/week) and strength, flexibility, and balance training. Health education included workshops on topics relevant to older adults and upper extremity stretching exercises.
settingLifestyle Interventions and Independence in Elders (LIFE) Study.
participantsCommunity-dwelling persons aged 70-89 with Short Physical Performance Battery scores less than 10 (N = 1,635). MEASUREMENTS: Dyspnea severity (defined as moderate to severe according to a Borg index >2 immediately after a 400-m walk), forced expiratory volume in 1 second (FEV1) (<lower limit of normal (LLN) defined low breathing capacity), and maximal inspiratory pressure (MIP) (<LLN defined respiratory muscle weakness) were assessed at baseline and 6, 18, and 30 months. Hospitalization for exacerbation of obstructive airways disease (EOAD) and pneumonia was also ascertained over the 42-month follow-up period.
resultsThe randomized groups were similar in baseline demographics, including mean age (79) and sex (67% female). The effect of physical activity on dyspnea severity, FEV1, and MIP was no different from that of health education but was associated with higher likelihood of respiratory hospitalization, significantly for EOAD (hazard ratio (HR) = 2.34, 95% confidence interval (CI) = 1.19-4.61, P = .01) and marginally for pneumonia (HR = 1.54, 95% CI = 0.98-2.42, P = .06).
conclusionIn older persons with mobility limitations, physical activity was associated with higher likelihood of respiratory hospitalization than health education, but differences in dyspnea severity, FEV1, and MIP did not accompany this effect-indicating that higher hospital use could be attributable to greater participant contact.
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Registered trials
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