SynthesisEndocrine2016
Risk factors of gestational diabetes mellitus recurrence: a meta-analysis.
Synthesis in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of risk factors for recurrent gestational diabetes mellitus.BMC pregnancy and childbirth · 2025Pooled it
- Gestational diabetes mellitus (GDM) in the first-reported pregnancy modifies association between interpregnancy-weight-change and GDM risk in the subsequent pregnancy.AJOG global reports · 2026Article
- Previous oral glucose tolerance test results as predictors of gestational diabetes mellitus in subsequent pregnancies: a retrospective cohort study.Nutrition & metabolism · 2026Article
- Early pregnancy body mass index outweighs gestational weight gain in predicting gestational diabetes mellitus: A single-center experience from Türkiye.Qatar medical journal · 2026Article
- Low early-pregnancy serum lipoprotein(a) as an independent associated factor for gestational diabetes mellitus: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- The recurrence risk of gestational diabetes according to the number of abnormal values in the oral glucose tolerance test.Acta obstetricia et gynecologica Scandinavica · 2025Article
- PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Maternal pre-pregnancy risks and postpartum consequences of gestational diabetes.Reproduction (Cambridge, England) · 2025Review
- The Maternal and Fetal Consequences of Metabolic Dysfunction-Associated Fatty Liver Disease and Gestational Diabetes Mellitus.Nutrients · 2025Review
- Is Breastfeeding an Effective Approach to Reduce Metabolic Risk After GDM in Mothers and Infants?Journal of clinical medicine · 2025Review
- Probiotic Supplementation during Pregnancy: Evaluating the Current Clinical Evidence against Gestational Diabetes Mellitus.Current diabetes reviews · 2025Review
- Gestational diabetes mellitus - more than the eye can see - a warning sign for future maternal health with transgenerational impact.Frontiers in clinical diabetes and healthcare · 2025Review
- Predicting recurrent gestational diabetes mellitus using artificial intelligence models: a retrospective cohort study.Archives of gynecology and obstetrics · 2024Article
- Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011-2018 data.Frontiers in nutrition · 2024Article
- Gestational diabetes in Germany-prevalence, trend during the past decade and utilization of follow-up care: an observational study.Scientific reports · 2023Observational
- Prediction of recurrent gestational diabetes mellitus: a retrospective cohort study.Archives of gynecology and obstetrics · 2023Article
- Maternal Gestational Diabetes Is Associated with High Risk of Childhood Overweight and Obesity: A Cross-Sectional Study in Pre-School Children Aged 2-5 Years.Medicina (Kaunas, Lithuania) · 2023Article
- Longer physical exercise duration prevents abnormal fasting plasma glucose occurrences in the third trimester: Findings from a cohort of women with gestational diabetes mellitus in Shanghai.Frontiers in endocrinology · 2023Article
- Multigenerational diabetes mellitus.Frontiers in endocrinology · 2023Review
- Number of parous events affects the association between physical exercise and glycemic control among women with gestational diabetes mellitus: A prospective cohort study.Journal of sport and health science · 2022Article
- Differing risk factors for new onset and recurrent gestational diabetes mellitus in multipara women: a cohort study.BMC endocrine disorders · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The literature regarding risk factors for gestational diabetes mellitus (GDM) recurrence is inconsistent. We aimed to assess the effect sizes of risk factors of GDM recurrence. We searched electronic databases (1970-2015) and bibliographies for studies that included women with GDM (index pregnancy) who had a consecutive birth. We compared the risk factors among women with and without GDM recurrence. Differences in variables measured on a continuous scale were estimated using the weighted mean difference (WMD). The standardized mean difference (SMD) was used to rate the pooled effects. For categorical variables, the pooled odds ratio was estimated. Cochran's Q test of heterogeneity was used to choose the model for estimating the pooled effects. Fourteen cross-sectional cohort studies (63 % with sample size ≥100) were considered. Women with GDM recurrence were older (by 1.32 years; P < 0.0001), heavier (by 1.82 BMI; P = 0.013), had higher 100-g oral glucose tolerance test (OGTT) levels (Fasting: by 8.42 mg/dl, 1-h: by 13.0 mg/dl, 2-h: by 18.2 mg/dl, 3-h: by 11.3 mg/dl; P < 0.0001 for all) and higher weight gain between pregnancies (by 3.24 kg; P = 0.012). The SMD effect sizes were relatively small (between 0.3 and 0.4), but weight gain between pregnancies had a medium-large effect size (SMD = 0.8). Insulin use, multiparity, and fetal macrosomia were all associated with GDM recurrence (OR 6.3 [95 % CI 3.9-10.2], OR 1.88 [95 % CI 1.09-3.24] and OR 1.63 [95 % CI 1.25-2.13], respectively). GDM recurrence is multifactorial. Stronger risk factors include insulin use, BMI, multiparity, macrosomia, and weight gain between pregnancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.