Evidence map›Paper›PMID 26999580›Full record

ArticleInternational journal of radiation biology2016

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

Lei Song, Nadia Falzone, Katherine A Vallis

Abstract read
In one paragraph

Article in International journal of radiation biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Small science · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Gold Nanoparticles Contact with Cancer Cell: A Brief Update.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lei Songa CR-UK/MRC Oxford Institute for Radiation Oncology, Department of Oncology , University of Oxford , Oxford , UK.
Nadia Falzonea CR-UK/MRC Oxford Institute for Radiation Oncology, Department of Oncology , University of Oxford , Oxford , UK.
Katherine A Vallisa CR-UK/MRC Oxford Institute for Radiation Oncology, Department of Oncology , University of Oxford , Oxford , UK.

Funding

Cancer Research UK 11564Cancer Research UK 16466Cancer Research UK C5255/A15935Medical Research Council
6 · The paper itself

Abstract

Purpose Radiolabeled antibodies and peptides hold promise for molecular radiotherapy but are often limited by a low payload resulting in inadequate delivery of radioactivity to tumour tissue and, therefore, modest therapeutic effect. We developed a facile synthetic method of radiolabeling indium-111 (

Indexed as

Cell SurvivalCoated Materials, BiocompatibleEpidermal Growth FactorErbB ReceptorsGoldHumansIndium RadioisotopesMCF-7 CellsMetal NanoparticlesMolecular Targeted TherapyNanocapsulesNeoplasms, ExperimentalRadiopharmaceuticalsTreatment OutcomeCoated Materials, BiocompatibleEGFR protein, humanEpidermal Growth FactorErbB ReceptorsGoldIndium RadioisotopesNanocapsulesRadiopharmaceuticalsAuger electron emittersEGFGold nanoparticlesIndium-111targeted radiotherapy

Identifiers

PMID26999580
PMCPMC5116916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.