Evidence map›Paper›PMID 26999579›Full record

ArticleNano letters2016

Complementary Metal-Oxide-Semiconductor Integrated Carbon Nanotube Arrays: Toward Wide-Bandwidth Single-Molecule Sensing Systems.

Steven B Warren, Sefi Vernick, Ethan Romano, Kenneth L Shepard

Abstract read
In one paragraph

Article in Nano letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven B WarrenDepartment of Electrical Engineering, Columbia University , New York, New York 10027, United States.
Sefi VernickDepartment of Electrical Engineering, Columbia University , New York, New York 10027, United States.
Ethan RomanoDepartment of Electrical Engineering, Columbia University , New York, New York 10027, United States.
Kenneth L ShepardDepartment of Electrical Engineering, Columbia University , New York, New York 10027, United States.

Funding

Translational CoreU19AI109761 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARIC, RALPH S · 2014 to 2018
$32.6M
Single Molecule Real Time Electronic SequencingR01HG006882 · NHGRI · INTEL LABS · PI LEMAY, SERGE GUY, SHEPARD, KENNETH L · 2012 to 2015
$5.0M
Studies of Riboswitch-Mediated Transcriptional Control Using Single-Molecule FielR01GM107417 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L, NUCKOLLS, COLIN P · 2014 to 2017
$1.5M
Integrated, multiplexed high-frequency electronic analysis of DNA in nanoporesR01HG006879 · NHGRI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEPARD, KENNETH L · 2012 to 2014
$1.4M
NHGRI NIH HHS R01 HG006879NHGRI NIH HHS R01 HG006882NIAID NIH HHS U19 AI109761NIAID NIH HHS U19AI109761NIGMS NIH HHS R01 GM107417NIGMS NIH HHS R01-GM107417
6 · The paper itself

Abstract

There is strong interest in realizing genomic molecular diagnostic platforms that are label-free, electronic, and single-molecule. One attractive transducer for such efforts is the single-molecule field-effect transistor (smFET), capable of detecting a single electronic charge and realized with a point-functionalized exposed-gate one-dimensional carbon nanotube field-effect device. In this work, smFETs are integrated directly onto a custom complementary metal-oxide-semiconductor chip, which results in an array of up to 6000 devices delivering a measurement bandwidth of 1 MHz. In a first exploitation of these high-bandwidth measurement capabilities, point functionalization through electrochemical oxidation of the devices is observed with microsecond temporal resolution, which reveals complex reaction pathways with resolvable scattering signatures. High-rate random telegraph noise is detected in certain oxidized devices, further illustrating the measurement capabilities of the platform.

Indexed as

SemiconductorsMetalsNanotubes, CarbonOxidesMetalsNanotubes, CarbonOxidescarbon nanotubeCMOSelectrochemical oxidationrandom telegraph noiseSingle-molecule

Identifiers

PMID26999579
PMCPMC5319850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.