Evidence map›Paper›PMID 26999472›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie2016

Trends in brain-dead organ donor characteristics: a 13-year analysis.

Mazen Hassanain, Eve Simoneau, Suhail A Doi, Murad Aljiffry, Abdulla Aloraini, Ahmad Madkhali, Peter Metrakos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Honoring the gift: The transformative potential of transplant-declined human organs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Mazen HassanainFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Eve SimoneauFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Suhail A DoiFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Murad AljiffryFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Abdulla AlorainiFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Ahmad MadkhaliFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Peter MetrakosFrom the Division of Hepato-Pancreatobiliary and Transplant Surgery, Department of Surgery, McGill University, Montreal, Que. (Hassanain, Aloraini, Metrakos); the Department of Surgery, King Saud University, Riyadh, Saudi Arabia (Hassanain, Madkhali); the Research School of Population Health, Australian National University, Canberra, Australia (Doi); and the Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia (Aljiffry).
Australian National University · AUKing Saud University · SAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDriven by disease trends, such as obesity and metabolic syndrome, that are increasingly prevalent in the general population, we aimed to evaluate the comorbidities and attributes of the brain-dead organ donor population over time in a longitudinal study.

methodsWe compared overall health and baseline attributes of organ donors between 2000-2005 and 2006-2012 using our prospective transplant database. Descriptive and comparative analyses of the 2 historical cohorts were performed.

resultsA total of 1040 brain-dead organ donors were included in our analysis: 496 from the 2000-2005 period and 544 from the 2006-2012 period. Our analysis revealed that donors from the recent (2006-2012) period were more likely to have increased body mass index (26.4 ± 6.0 v. 25.0 ± 4.8, p = 0.003), smoking history (57.0% v. 27.2%, p < 0.001), coronary artery disease (14.3% v. 3.2%, p = 0.015) and dyslipidemia (19.1% v. 4.2%, p < 0.001), but less likely to have concurrent infection (1.1% v. 7.9%, p < 0.001) than those from the earlier period.

conclusionOur data suggest that the characteristics and comorbidities of brain-dead organ donors have somewhat deteriorated over the last decade. Further studies are needed to evaluate the impact of these health attributes on donated organ utilization and outcomes.

Indexed as

Body Mass IndexBrain DeathAdultComorbidityDyslipidemiasFemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedQuebecSmokingTissue Donors

Identifiers

PMID26999472
PMCPMC4982859
OpenAlexW2470737382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.