Evidence map›Paper›PMID 26999438›Full record

ArticleAddiction (Abingdon, England)2016

The indirect effects of childhood attention deficit hyperactivity disorder on alcohol problems in adulthood through unique facets of impulsivity.

Sarah L Pedersen, Christine A P Walther, Seth C Harty, Elizabeth M Gnagy, William E Pelham, Brooke S G Molina

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Alcohol and cannabis use predicted by affect-urgency interactions in everyday life.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  4. Article
  5. ADHD in adults: despite evidence sufficient to guide diagnosis and treatment, many questions remain.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sarah L PedersenUniversity of Pittsburgh, Pittsburgh, PA, USA.
Christine A P WaltherUniversity of Houston-Clear Lake, Houston, TX, USA.
Seth C HartyChatham University, Pittsbugh, PA, USA.
Elizabeth M GnagyFlorida International University, Miami, FL, USA.
William E PelhamFlorida International University, Miami, FL, USA.
Brooke S G MolinaUniversity of Pittsburgh, Pittsburgh, PA, USA.
Florida International University · USUniversity of Pittsburgh · USChatham University · USUniversity of Houston - Clear Lake · US

Funding

FAMILY AND PEER RISK FACTORS FOR PREADOLESCENT DRINKINGR01AA012342 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOVAN, JOHN E. · 2000 to 2015
$9.8M
DEVELOPMENT OF ALCOHOL USE AND ABUSE IN ADHD ADOLESCENTSR01AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 1998 to 2007
$8.5M
The Development of Alcohol Use and Abuse in ADHD Adolescents and Young AdultsR37AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2008 to 2017
$7.9M
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)R01NS039087 · NINDS · UNIVERSITY OF CINCINNATI · PI SALLEE, FLOYD R · 2000 to 2005
$5.7M
VALIDITY OF DSM-N SUBTYPES OF ADHD FOR YOUNG CHILDRENR01MH053554 · NIMH · UNIVERSITY OF CHICAGO · PI LAHEY, BENJAMIN B · 1995 to 2009
$4.2M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
Behavior Modification and Young ADHD ChildrenR01MH069614 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E · 2005 to 2009
$3.0M
Development of Drug Use and Abuse in ADHD AdolescentsR01DA012414 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E · 2001 to 2012
$2.2M
ADHD Treatment:Comparative and Combined Dosage EffectsR01MH062946 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E · 2001 to 2004
$2.0M
Inhibitory control and clinical response in ADHDR01MH069434 · NIMH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI HAWK, LARRY W · 2005 to 2009
$1.8M
Positive Illusions in ADHD: Processes and ConsequencesR01MH065899 · NIMH · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HOZA, BETSY · 2004 to 2007
$1.7M
2/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077676 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2008 to 2011
$1.6M
NIAAA NIH HHS K01 AA021135NIAAA NIH HHS K21 AA000202NIAAA NIH HHS R01 AA011873NIAAA NIH HHS R01 AA012342NIAAA NIH HHS R37 AA011873NIAAA NIH HHS R56 AA011873NIAAA NIH HHS T32 AA007453NIDA NIH HHS N01 DA085553NIDA NIH HHS R01 DA012414NIDA NIH HHS R21 DA016631NIMH NIH HHS N01 MH012010NIMH NIH HHS R01 MH053554NIMH NIH HHS R01 MH062946NIMH NIH HHS R01 MH065899NIMH NIH HHS R01 MH069434NIMH NIH HHS R01 MH069614NIMH NIH HHS R01 MH077676NIMH NIH HHS U01 MH050467NINDS NIH HHS R01 NS039087
6 · The paper itself

Abstract

BACKGROUND AND

aimsResearch has not studied unique impulsivity dimensions as prospective links between childhood attention deficit hyperactivity disorder (ADHD) and alcohol problems. We examined the association between childhood ADHD, five facets of impulsivity and alcohol problems in adulthood and the indirect effects of childhood ADHD-to-impulsivity-to-alcohol problems. DESIGN, SETTING AND

participantsParticipants were from a longitudinal study (n = 289, meanage  = 28.67) of individuals with (n = 170) and without (n = 119) childhood ADHD. The ADHD sample, as part of an ADHD summer treatment program, was diagnosed initially in childhood (1987-96, Pittsburgh, PA, USA) via structured parent interview and standardized parent/teacher ratings. The ADHD sample and demographically similar individuals without ADHD (living in the greater Pittsburgh area) were recruited to participate in the Pittsburgh ADHD Longitudinal Study (PALS) between 1999 and 2003. MEASUREMENTS: Self-reported impulsivity (UPPS-P) and alcohol-related problems were assessed in adulthood (2011-14).

findingsAdults with, compared with those without, childhood ADHD had more alcohol problems (β = 0.34, P < 0.05) and higher levels of negative urgency, positive urgency, lack of perseverance and lack of planning (βs = 0.24-0.31, Ps < 0.001). Impulsivity facets (except sensation-seeking) were related to number of alcohol problems (βs = 0.34-0.61, Ps < 0.05). Negative (β = 0.26, P < 0.01) and positive (β = 0.27, P < 0.01) urgency mediated the association between childhood ADHD and number of adult alcohol problems.

conclusionsElevated levels of emotional impulsivity (negative/positive urgency) may place children with attention deficit hyperactivity disorder at increased risk for alcohol problems in adulthood.

Indexed as

Impulsive BehaviorAdolescentAdultAlcohol-Related DisordersAttention Deficit Disorder with HyperactivityCase-Control StudiesChildChild, PreschoolFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleProspective StudiesUnited StatesYoung AdultADDADHDalcoholalcohol problemsemotional impulsivityimpulsivitynegative urgencypositive urgency

Identifiers

PMID26999438
PMCPMC4983236
OpenAlexW2409180639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.