Evidence map›Paper›PMID 26999221›Full record

ReviewPathogens (Basel, Switzerland)2016

The Host's Reply to Candida Biofilm.

Jeniel E Nett

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Critical reviews in microbiology · 2021
    Review
  6. Pathogenesis and Clinical Relevance ofFrontiers in microbiology · 2020
    Review
  7. Antimicrobial effect onLaser therapy · 2019
    Article
  8. Neutrophil extracellular traps in fungal infection.Seminars in cell & developmental biology · 2019
    Review
  9. Candida parapsilosis: from Genes to the Bedside.Clinical microbiology reviews · 2019
    Review
  10. Article
  11. Methodologies forMicrobial cell (Graz, Austria) · 2018
    Review
  12. Review
  13. Article
  14. Frontiers in medicine · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Immune Recognition of Fungal Polysaccharides.Journal of fungi (Basel, Switzerland) · 2017
    Review
  19. Fungal Biofilms: Inside Out.Microbiology spectrum · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeniel E NettUniversity of Wisconsin-Madison, Departments of Medicine, Medical Microbiology and Immunology, 5203 Microbial Sciences Building, 1550 Linden Drive, Madison, WI 53706, USA. jenett@medicine.wisc.edu.

Funding

Mechanisms of Candida Biofilm Immune EvasionK08AI108727 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI NETT, JENIEL E · 2014 to 2018
$960k
NIAID NIH HHS K08 AI108727
6 · The paper itself

Abstract

Candida spp. are among the most common nosocomial fungal pathogens and are notorious for their propensity toward biofilm formation. When growing on a medical device or mucosal surface, these organisms reside as communities embedded in a protective matrix, resisting host defenses. The host responds to Candida biofilm by depositing a variety of proteins that become incorporated into the biofilm matrix. Compared to free-floating Candida, leukocytes are less effective against Candida within a biofilm. This review highlights recent advances describing the host's response to Candida biofilms using ex vivo and in vivo models of mucosal and device-associated biofilm infections.

Indexed as

biofilmCandidadefensehostmatrixmodelmonocytemucosalneutrophil

Identifiers

PMID26999221
PMCPMC4810154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.