Evidence map›Paper›PMID 26999183›Full record

ArticleInternational journal of environmental research and public health2016

Polyethyleneimine Capped Silver Nanoclusters as Efficient Antibacterial Agents.

Dong Xu, Qingyun Wang, Tao Yang, Jianzhong Cao, Qinlu Lin, Zhiqin Yuan, Le Li

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong XuNational Engineering Laboratory for Rice and By-Products Further Processing, Central South University of Forestry & Technology, Changsha 410004, China. philip198349@gmail.com.
Qingyun WangNational Engineering Laboratory for Rice and By-Products Further Processing, Central South University of Forestry & Technology, Changsha 410004, China. jalywang6688@163.com.
Tao YangNational Engineering Laboratory for Rice and By-Products Further Processing, Central South University of Forestry & Technology, Changsha 410004, China. yangtao807@163.com.
Jianzhong CaoNational Engineering Laboratory for Rice and By-Products Further Processing, Central South University of Forestry & Technology, Changsha 410004, China. cjz2007@hotmail.com.
Qinlu LinNational Engineering Laboratory for Rice and By-Products Further Processing, Central South University of Forestry & Technology, Changsha 410004, China. LinQL0403@126.com.
Zhiqin YuanState Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China. yuanzq@mail.buct.edu.cn.
Le LiHunan Ehome Health Technology Inc., Buliding 6# 1715, LvDi Central Square, Yuelu District, Changsha 410023, China. simonli111@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of efficient antibacterial agents is critical for human health. In the present study, we investigated the antibacterial activity of polyethyleneimine (PEI)-capped silver nanoclusters (PEI-AgNCs), based on the fact that nanoclusters normally have higher surface-to-volume ratios than traditional nanomaterials and PEI itself has a strong antimicrobial capacity. We synthesized stable silver nanoclusters by altering PEI molecular weight from 0.6 kDa to 25 kDa and characterized them by UV-Vis absorption and fluorescence spectroscopy and high resolution transmission electron microscopy. The sizes of AgNCs were around 2 nm in diameter and were little influenced by the molecular weight of PEIs. The antibacterial abilities of the four PEI-AgNCs were explored on agar plate and in liquid systems. Our results revealed that the antibacterial activity of PEI-AgNCs is excellent and the reduction of PEI molecular weight could result in the increased antibacterial capacity of PEI-AgNCs. Such proposed new materials might be useful as efficient antibacterial agents in practical clinical applications.

Indexed as

Anti-Bacterial AgentsDrug Delivery SystemsEscherichia coliEscherichia coli InfectionsHumansMetal NanoparticlesPolyethyleneimineSilverAnti-Bacterial AgentsPolyethyleneimineSilverantibacterial agentpolyethyleneiminesilver nanoclusters

Identifiers

PMID26999183
PMCPMC4808997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.