Evidence map›Paper›PMID 26999178›Full record

Trial reportInternational journal of environmental research and public health2016

Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers.

Marina Gradiser, Martina Matovinovic Osvatic, Dario Dilber, Ines Bilic-Curcic

Abstract readClinical Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Is fingerprint ridge density influenced by hand dimensions?Acta bio-medica : Atenei Parmensis · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina GradiserCounty Hospital Cakovec, I.G. Kovacica 1E, 40000 Cakovec, Croatia. marina.gradiser@gmail.com.
Martina Matovinovic OsvaticDepartment of Endocrinology, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia. martina1000@yahoo.com.
Dario DilberCounty Hospital Cakovec, I.G. Kovacica 1E, 40000 Cakovec, Croatia. dario.dilber@gmail.com.
Ines Bilic-CurcicFaculty of Medicine, University Josip JurajStrossmayer, Department of Pharmacology, Clinical Hospital Center Osijek, 31000 Osijek, Croatia. ibcurcic@mefos.hr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess environmental and hereditary influence on development of pituitary tumors using dermatoglyphic traits. The study was performed on 126 patients of both genders with pituitary tumors (60 non-functional and 66 functional pituitary tumor patients) in comparison to the control group of 400 phenotypically healthy individuals. Statistical analysis of quantitative and qualitative traits of digito-palmar dermatoglyphics was performed, and hormonal status was determined according to the standard protocols. Although we did not find markers that could specifically distinguish functional from non-functional tumors, we have found markers predisposing to the development of tumors in general (a small number of ridges between triradius of both hands, a smaller number of ridges between the triradius of c-d rc R), those for endocrine dysfunction (increased number of arches and reduced number of whorls, difference of pattern distribution in the I3 and I4 interdigital space), and some that could potentially be attributed to patients suffering from pituitary tumors (small number of ridges for variables FRR 5, smaller number of ridges in the FRL 4 of both hands and difference of pattern distribution at thenar of I1 and I2 interdigital space). The usage of dermatoglyphic traits as markers of predisposition of pituitary tumor development could facilitate the earlier detection of patients in addition to standard methods, and possibly earlier treatment and higher survival rate. Finally, our results are consistent with the hypothesis about multifactorial nature of pituitary tumor etiology comprised of both gene instability and environmental factors.

Indexed as

DermatoglyphicsEnvironmentGenetic Predisposition to DiseaseAdenomaAdultCase-Control StudiesCross-Sectional StudiesEarly Detection of CancerFemaleHumansMaleMiddle AgedPhenotypePituitary Neoplasmsdermatoglyphic traitsearly detectionfunctional pituitary tumorsmultifactorial etiologynon-functional pituitary tumors

Identifiers

PMID26999178
PMCPMC4808993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.