Evidence map›Paper›PMID 26998525›Full record

ArticleInternational journal of cancer research and molecular mechanisms2015

Cell Differentiation and Checkpoint.

Sara Cuesta Sancho, Toru Ouchi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer research and molecular mechanisms, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sara Cuesta SanchoDepartment of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY14263, USA.
Toru OuchiDepartment of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY14263, USA.
Roswell Park Comprehensive Cancer Center · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Model of Tumor Suppression by BRCA1R01CA090631 · NCI · NORTHSHORE UNIVERSITY HEALTHSYSTEM · PI OUCHI, TORU · 2002 to 2011
$2.7M
REGULATION OF P53 FUNCTION BY BRCA1 TUMOR SUPPRESSORR01CA079892 · NCI · NORTHSHORE UNIVERSITY HEALTHSYSTEM · PI OUCHI, TORU · 1999 to 2008
$1.8M
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA079892NCI NIH HHS R01 CA090631
6 · The paper itself

Abstract

DNA damage is induced in many types of cells by internal and external cell stress. When DNA is damaged, DNA Damage Response (DDR) programs are activated to repair the DNA lesions in order to preserve genomic integrity and suppress subsequent malignant transformation. Among these programs is cell cycle checkpoint that ensures cell cycle arrest and subsequent repair of the damaged DNA, apoptosis and senescence in various phases of the cell cycle. Moreover, recent studies have established the cell differentiation checkpoint, the other type of the checkpoint that is specifically activated in the course of differentiation. We will discuss the evidences that support the link between DNA damage proteins and C2C12 cell differentiation.

Indexed as

C2C12CheckpointsDifferentiationDNA damage response

Identifiers

PMID26998525
PMCPMC4795824
OpenAlexW2416659111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.