ArticleJournal of diabetes research2016
Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection.
Article in Journal of diabetes research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Sex difference for the risk of amputation in diabetic patients: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Higher C-reactive protein/albumin ratio is a potential marker for predicting amputation in patients with diabetic foot infection.Archives of endocrinology and metabolism · 2025Review
- Altered expression of miR-132, miR-155, VEGF, and IGF-1 as key indicators in the pathogenesis of diabetic foot infection.American journal of translational research · 2025Article
- Preoperative Antibiotic Administration Does Not Improve the Outcomes of Operated Diabetic Foot Infections.Antibiotics (Basel, Switzerland) · 2024Article
- Therapy for Non-Diabetic Foot Infections After Orthopedic Foot and Ankle Surgery: The Duration of Post-Debridement Antibiotic Treatment Does Not Alter Failure Risk.Life (Basel, Switzerland) · 2024Article
- Prevalence and risk factors of wound complications after transtibial amputation in patients with diabetic foot.World journal of diabetes · 2024Article
- Clinical efficacy of antibiotic-loaded bone cement and negative pressure wound therapy in multidrug-resistant organisms diabetic foot ulcers: a retrospective analysis.Frontiers in cellular and infection microbiology · 2024Article
- [Characteristics of Inflammatory Markers in Diabetic Foot Patients and Their Relationship With Prognosis of Diabetic Foot Ulcers].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Article
- An Overview of Risk Factors for Diabetic Foot Amputation: An Observational, Single-centre, Retrospective Cohort Study.TouchREVIEWS in endocrinology · 2023Article
- Distribution of Causative Microorganisms in Diabetic Foot Infections: A Ten-Year Retrospective Study in a Tertiary Care Hospital in Central Malaysia.Antibiotics (Basel, Switzerland) · 2023Article
- Deriving International Classification of Diseases, 9th and 10th revision, codes for identifying and following up patients with diabetic lower extremity ulcers.Journal of vascular surgery cases and innovative techniques · 2022Article
- Indirect impact of the COVID-19 pandemic on diabetes-related lower extremity amputations: A regional study.Joint diseases and related surgery · 2022Article
- Article
- The effects of dietary/herbal supplements and the serum levels of micronutrients on the healing of diabetic foot ulcers in animal and human models: a systematic review.Journal of diabetes and metabolic disorders · 2021Review
- Antibiotic resistance in diabetic foot infection: how it changed with COVID-19 pandemic in a tertiary care center.Diabetes research and clinical practice · 2021Article
- Psychometric evaluation of the Persian version of the diabetic foot self-care questionnaire in Iranian patients with diabetes.BMC endocrine disorders · 2021Article
- Clinical profiles of diabetic foot ulcer patients undergoing major limb amputation at a tertiary care center in North-eastern Tanzania.BMC surgery · 2021Article
- Comparison of WIFi, University of Texas and Wagner Classification Systems as Major Amputation Predictors for Admitted Diabetic Foot Patients: A Prospective Cohort Study.Malaysian orthopaedic journal · 2020Article
- Prevalence and interrelationships of foot ulcer, risk-factors and antibiotic resistance in foot ulcers in diabetic populations: A systematic review and meta-analysis.World journal of diabetes · 2020Article
- Antimicrobial Susceptibility Testing and Phenotypic Detection of MRSA Isolated from Diabetic Foot Infection.International journal of general medicine · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to identify and quantify risk factors for amputation in diabetic patients hospitalized for foot infections. This cross-sectional study comprised 100 patients with diabetic infectious complications in the lower limbs. The variables investigated were related to diabetes, infection, and treatment compliance. Multiple Cox regression analysis was performed to identify the variables independently associated with the outcome of amputation. The most prevalent chronic complications were neuropathy and hypertension. Most patients presented with a neuroischemic foot (86%). The Morisky test showed that 72% were not compliant with diabetes treatment. Regarding patient outcome, 61% progressed to amputation, 14% to debridement, and 9% to revascularization. The results showed a 42% higher risk for progression to amputation in patients with previous use of antimicrobials. Also, the amputation risk was 26% higher for those less compliant with diabetes treatment. An increase of one point in the Wagner ulcer classification criteria corresponded to a 65% increase in the risk of amputation. Undergoing conservative, nonsurgical procedures prior to admission provided a 63% reduction in the risk of amputation. Knowledge of these factors is critical to enable multidisciplinary teams to develop treatment plans for these patients so as to prevent the need for amputation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.