Evidence map›Paper›PMID 26998261›Full record

ArticleBiomedical reports2016

Prostate cancer markers: An update.

Srinivas Pentyala, Terry Whyard, Sahana Pentyala, John Muller, John Pfail, Sunjit Parmar, Carlos G Helguero, Sardar Khan

Abstract read
In one paragraph

Article in Biomedical reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
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  9. LMNB1, a potential marker for early prostate cancer progression.American journal of cancer research · 2022
    Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Srinivas PentyalaDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Urology, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Health Sciences, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Physiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
Terry WhyardDepartment of Urology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
Sahana PentyalaDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
John MullerDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
John PfailDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
Sunjit ParmarDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
Carlos G HelgueroDepartment of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.
Sardar KhanDepartment of Urology, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Physiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the most common noncutaneous malignancy in American men, prostate cancer currently accounts for 29% of all diagnosed cancers, and ranks second as the cause of cancer fatality in American men. Prostatic cancer is rarely symptomatic early in its course and therefore disease presentation often implies local extension or even metastatic disease. Thus, it is extremely critical to detect and diagnose prostate cancer in its earliest stages, often prior to the presentation of symptoms. Three of the most common techniques used to detect prostate cancer are the digital rectal exam, the transrectal ultrasound, and the use of biomarkers. This review presents an update regarding the field of prostate cancer biomarkers and comments on future biomarkers. Although there is not a lack of research in the field of prostate cancer biomarkers, the discovery of a novel biomarker that may have the advantage of being more specific and effective warrants future scientific inquiry.

Indexed as

biomarkersGleason scoresmetastasisprostate cancerprostatectomy

Identifiers

PMID26998261
PMCPMC4774403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.