ArticleSupramolecular chemistry
ITC and NMR Analysis of the Encapsulation of Fatty Acids within a Water-Soluble Cavitand and its Dimeric Capsule.
Article in Supramolecular chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Purely Covalent Molecular Cages and Containers for Guest Encapsulation.Chemical reviews · 2022Review
- The thermodynamics of guest complexation to octa-acid and tetra-Supramolecular chemistry · 2019Article
- Binding free energies in the SAMPL6 octa-acid host-guest challenge calculated with MM and QM methods.Journal of computer-aided molecular design · 2018Article
- Lipid bilayer environments control exchange kinetics of deep cavitand hosts and enhance disfavored guest conformations.Chemical science · 2018Article
- Origin and Formation Mechanism Investigation of Compound Precipitation from the Traditional Chinese Prescription Huang-Lian-Jie-Du-Tang by Isothermal Titration Calorimetry.Molecules (Basel, Switzerland) · 2017Article
- Predicting Binding Free Energies: Frontiers and Benchmarks.Annual review of biophysics · 2017Review
- Binding of carboxylate and trimethylammonium salts to octa-acid and TEMOA deep-cavity cavitands.Journal of computer-aided molecular design · 2017Article
- Binding Hydrated Anions with Hydrophobic Pockets.Journal of the American Chemical Society · 2016Article
- From steroids to aqueous supramolecular chemistry: an autobiographical career review.Beilstein journal of organic chemistry · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We report here NMR and ITC studies of the binding of ionizable guests (carboxylate acids) to a deep-cavity cavitand. These studies reveal that the shortest guests favored 1:1 complex formation, but the longer the alkyl chain the more the 2:1 host-guest capsule is favored. For intermediate-sized guests, the equilibrium between these two states is controlled by pH; at low values the capsule containing the carboxylic acid guest is favored, whereas as the pH is raised deprotonation of the guest favors the 1:1 complex. Interestingly, for one host-guest pair the energy required to de-cap the 2:1 capsular complex and form the 1:1 complex is sufficient to shift the p
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.