Evidence map›Paper›PMID 26997215›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Impact of pediatric inflammatory bowel disease on linear growth: Data from a national cohort study in Saudi Arabia.

Mohammad I El Mouzan, Mohammad A Al Mofarreh, Omar I Saadah, Abdulrahman A Al-Hussaini, Khalid A Al-Saleem, Ali I Al Mehaidib

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
  2. Article
  3. Saudi consensus guidance for the management of inflammatory bowel disease during pregnancy.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2023
    Article
  4. Article
  5. [Inflammatory bowel disease with growth hormone deficiency in adolescents: an analysis of 4 cases and literature review].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Review
  6. Growth parameters early in the course of pediatric inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  7. Natural history and outcome of inflammatory bowel diseases in children in Saudi Arabia: A single-center experience.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  8. Impact of pediatric inflammatory bowel disease on linear growth: Data from a national cohort study in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  9. Impact of pediatric inflammatory bowel disease on linear growth: Data from a national cohort study in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mohammad I El MouzanDepartment of Pediatrics, Head, Pediatric Inflammatory Bowel Disease Research Group, Member of Prince Abdullah Bin Khalid Celiac Disease Research Chair, King Saud University, Riyadh, Saudi Arabia.
Mohammad A Al Mofarreh
Omar I Saadah
Abdulrahman A Al-Hussaini
Khalid A Al-Saleem
Ali I Al Mehaidib
King Abdul Aziz University Hospital · SAKing Faisal Specialist Hospital & Research Centre · SAKing Fahd Medical City · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimLinear growth impairment (LGI) is one of the most important features peculiar to children with inflammatory bowel disease (IBD). The aim of this report is to define the impact of IBD on the linear growth of children in the Kingdom of Saudi Arabia (KSA). SETTING AND

designMulticenter retrospective study. PATIENTS AND

methodsData from a cohort of newly- diagnosed children with IBD from 2003 to 2012 were analyzed retrospectively. The diagnosis of IBD was confirmed in accordance with the published criteria. Length/height for age was measured at diagnosis. The World Health Organization (WHO) reference was used and LGI was defined by length/height for age <-2 standard deviation. Chi-square test was used to test the significance of estimates and a P < 0.05 was considered significant.

resultsThere were 374 children from 0.33 to 16 years of age, including 119 ulcerative colitis (UC) (32%), and 255 Crohn's disease (CD) (68%) patients. The prevalence of LGI was 26%, 28%, and 21% in IBD, CD, and UC, respectively. In children below 10 years, LGI was significantly more common in CD (P = 0.010), while in UC children, it was more common in older children (P = 0.011).

conclusionThis study demonstrates a prevalence of LGI consistent with that reported in the literature, but higher in CD children with early onset (<10 years) and in older children with UC, underscoring the importance of monitoring growth in children with IBD in the Saudi population. Prospective studies are needed to define the impact of IBD on growth velocity, puberty, and final adult stature.

Indexed as

AdolescentAge FactorsChildChild, PreschoolCohort StudiesFemaleGrowth DisordersHumansInfantInflammatory Bowel DiseasesMaleRetrospective StudiesSaudi ArabiaSex Factors

Identifiers

PMID26997215
PMCPMC4817292
OpenAlexW2293752864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.