ArticleNature communications2016
A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 107 citations in OpenAlex.
- Achieving high molecular weight alternating copolymers of 1-octene with methyl acrylateRSC advances · 2024Article
- Diazido macrocyclic sulfates as a platform for the synthesis of sequence-defined polymers for antibody drug conjugates.Chemical science · 2022Article
- Reading mixtures of uniform sequence-defined macromolecules to increase data storage capacity.Communications chemistry · 2020Article
- Dual sequence definition increases the data storage capacity of sequence-defined macromolecules.Communications chemistry · 2020Article
- High-density information storage in an absolutely defined aperiodic sequence of monodisperse copolyester.Nature communications · 2020Article
- Sequence-Defined Macrocycles for Understanding and Controlling the Build-up of Hierarchical Order in Self-Assembled 2D Arrays.Journal of the American Chemical Society · 2019Article
- Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving.Nature chemistry · 2019Article
- Synthesis of polymers with on-demand sequence structures via dually switchable and interconvertible polymerizations.Nature communications · 2018Article
- Ultra-Low Dispersity Poly(vinyl alcohol) Reveals Significant Dispersity Effects on Ice Recrystallization Inhibition Activity.ACS macro letters · 2017Article
- Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation.Nature communications · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a growing interest in sequence-controlled polymers toward advanced functional materials. However, control of side-chain order for vinyl polymers has been lacking feasibility in the field of polymer synthesis because of the inherent feature of chain-growth propagation. Here we show a general and versatile strategy to control sequence in vinyl polymers through iterative radical cyclization with orthogonally cleavable and renewable bonds. The proposed methodology employs a repetitive and iterative intramolecular cyclization via a radical intermediate in a one-time template with a radical-generating site at one end and an alkene end at the other, each of which is connected to a linker via independently cleavable and renewable bonds. The unique design specifically allowed control of radical addition reaction although inherent chain-growth intermediate (radical species) was used, as well as the iterative cycle and functionalization for resultant side chains, to lead to sequence-controlled vinyl polymers (or oligomers).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.