ArticleBMC cancer2016
Hair dye use, regular exercise, and the risk and prognosis of prostate cancer: multicenter case-control and case-only studies.
Article in BMC cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association of physical activity with urological cancer risk: a systematic review and meta-analysis.Nature communications · 2026Pooled it
- Association between hair dye use and human cancers: A systematic review.JAAD international · 2026Review
- Serum metabolomic profile of hair dye use.Scientific reports · 2023Article
- Risk of Carcinogenicity Associated with Synthetic Hair Dyeing Formulations: A Biochemical View on Action Mechanisms, Genetic Variation and Prevention.Indian journal of clinical biochemistry : IJCB · 2022Review
- Article
- Personal use of permanent hair dyes and cancer risk and mortality in US women: prospective cohort study.BMJ (Clinical research ed.) · 2020Article
- Physical Activity and Mortality in Cancer Survivors: A Systematic Review and Meta-Analysis.JNCI cancer spectrum · 2020Article
- The Bio-Safety Concerns of Three Domestic Temporary Hair Dye Molecules: Fuchsin Basic, Victoria Blue B and Basic Red 2.Molecules (Basel, Switzerland) · 2019Article
- Total energy expenditure and vigorous-intensity physical activity are associated with reduced odds of reclassification among men on active surveillance.Prostate cancer and prostatic diseases · 2018Article
- Does hair dye use really increase the risk of prostate cancer?BMC cancer · 2017Article
- Preparation and Application of Carboxylated Graphene Oxide Sponge in Dye Removal.International journal of environmental research and public health · 2017Article
- Lower SHBG level is associated with higher leptin and lower adiponectin levels as well as metabolic syndrome, independent of testosterone.Scientific reports · 2017Article
- Effects of exercise training on breast cancer metastasis in a rat model.International journal of experimental pathology · 2017Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigated the effects that hair dye use and regular exercise exert on the risk and prognosis of prostate cancer.
methodsWe studied 296 cases of histologically confirmed prostate cancer and 296 age- (in 2-y bands), ethnicity-, and hospital-matched controls in Taiwan between August 2000 and December 2008. To determine the rate of prostate cancer survival, another 608 incident prostate cancer cases occurring between August 2000 and December 2007 were investigated. Information on hair dye use and regular exercise was obtained using a standardized questionnaire.
resultsThe use of hair dyes was associated with a significant 2.15-fold odds of developing prostate cancer (adjusted odds ratio = 2.15, 95% confidence interval [CI] = 1.32-3.57), but was not associated with prostate cancer survival, compared with no use. The significant risks were more prominent in users aged < 60 years who had used hair dyes for > 10 years, > 6 times per year, and started using hair dyes before 1980. By contrast, regular exercise significantly reduced the number of prostate-cancer-specific death (adjusted hazard ratio = 0.37, 95% CI = 0.16-0.83); the protective effect of exercise was more prominent among cancer patients who exercised daily (≥ 7 times/week). However, exercise could not prevent the development of prostate cancer.
conclusionsHair dye use increased the risk of prostate cancer, whereas regular exercise reduced the number of prostate-cancer-specific deaths.
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