Evidence map›Paper›PMID 26996067›Full record

ArticleCellular & molecular immunology2017

Impaired T-cell differentiation in diabetic foot ulceration.

João Moura, João Rodrigues, Marta Gonçalves, Cláudia Amaral, Margarida Lima, Eugénia Carvalho

Open access · bronzeAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 93 citations in OpenAlex.

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  17. Pathology of Diabetes-Induced Immune Dysfunction.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

João MouraCenter for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal.
João RodriguesHospital de Santo António (HSA), Centro Hospitalar do Porto (CHP), 4099-001 Porto, Portugal.
Marta GonçalvesHospital de Santo António (HSA), Centro Hospitalar do Porto (CHP), 4099-001 Porto, Portugal.
Cláudia AmaralHospital de Santo António (HSA), Centro Hospitalar do Porto (CHP), 4099-001 Porto, Portugal.
Margarida LimaHospital de Santo António (HSA), Centro Hospitalar do Porto (CHP), 4099-001 Porto, Portugal.
Eugénia CarvalhoCenter for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal.
Centro Hospitalar do Porto · PTArkansas Children's Hospital · USHospital de Santo António · PTUniversidade do Porto · PTUniversity of Coimbra · PT

Funding

RESOURCE CORE 3: ANALYTICAL COREP30AG028718 · NIA · UNIV OF ARKANSAS FOR MED SCIS · PI WEI, JEANNE Y · 2011 to 2015
$5.1M
Effects of amino acids on regional lipid metabolismR01AG033761 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BORSHEIM, ELISABET · 2009 to 2013
$1.6M
NIA NIH HHS P30 AG028718NIA NIH HHS R01 AG033761
6 · The paper itself

Abstract

Foot ulceration is one of the most debilitating complications associated with diabetes, but its cause remains poorly understood. Several studies have been undertaken to understand healing kinetics or find possible therapies to enhance healing. However, few studies have been directed at understanding the immunological alterations that could influence wound healing in diabetes. In this study, we analysed the T-cell receptor (TCR) repertoire diversity in TCR-αβ

Indexed as

Cell DifferentiationAdultClone CellsCytokinesDiabetic FootFemaleFlow CytometryGenetic LociGenetic VariationHumansInflammationLymphocyte ActivationMaleMiddle AgedReceptors, Antigen, T-Cell, alpha-betaReceptors, ChemokineCytokinesReceptors, Antigen, T-Cell, alpha-betaReceptors, Chemokine

Identifiers

PMID26996067
PMCPMC5596240
OpenAlexW2315578124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.