ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2016
Functional Connectivity During Exposure to Favorite-Food, Stress, and Neutral-Relaxing Imagery Differs Between Smokers and Nonsmokers.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The cerebellum plays more than one role in the dysregulation of appetite: Review of structural evidence from typical and eating disorder populations.Brain and behavior · 2023Pooled it
- Immediate and sustained effects of acupuncture on the default mode network.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Functional magnetic resonance imaging of depression: a bibliometrics and meta-analysis.Annals of general psychiatry · 2024Article
- Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders.Addictive behaviors · 2024Article
- A Network Analysis of Cigarette Craving.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Article
- Effects of Smoking Status and State on Intrinsic Connectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Graph theory analysis of whole brain functional connectivity to assess disturbances associated with suicide attempts in bipolar disorder.Translational psychiatry · 2022Article
- Health-Promoting Behaviors, Health Literacy, and Levels of Knowledge about Smoking-Related Diseases among Smokers and Non-smokers: A Cross-Sectional Study.Tuberculosis and respiratory diseases · 2021Article
- Tobacco Smoking, Eating Behaviors, and Body Weight: A Review.Current addiction reports · 2019Article
- Neurobiological Considerations for Tobacco Use Disorder.Current behavioral neuroscience reports · 2018Article
- Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents.Drug and alcohol dependence · 2017Article
- Cingulate cortex functional connectivity predicts future relapse in alcohol dependent individuals.NeuroImage. Clinical · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
introductionTobacco-use disorder is a complex condition involving multiple brain networks and presenting with multiple behavioral correlates including changes in diet and stress. In a previous functional magnetic resonance imaging (fMRI) study of neural responses to favorite-food, stress, and neutral-relaxing imagery, smokers versus nonsmokers demonstrated blunted corticostriatal-limbic responses to favorite-food cues. Based on other recent reports of alterations in functional brain networks in smokers, the current study examined functional connectivity during exposure to favorite-food, stress, and neutral-relaxing imagery in smokers and nonsmokers, using the same dataset.
methodsThe intrinsic connectivity distribution was measured to identify brain regions that differed in degree of functional connectivity between groups during each imagery condition. Resulting clusters were evaluated for seed-to-voxel connectivity to identify the specific connections that differed between groups during each imagery condition.
resultsDuring exposure to favorite-food imagery, smokers versus nonsmokers showed lower connectivity in the supramarginal gyrus, and differences in connectivity between the supramarginal gyrus and the corticostriatal-limbic system. During exposure to neutral-relaxing imagery, smokers versus nonsmokers showed greater connectivity in the precuneus, and greater connectivity between the precuneus and the posterior insula and rolandic operculum. During exposure to stress imagery, smokers versus nonsmokers showed lower connectivity in the cerebellum.
conclusionsThese findings provide data-driven insights into smoking-related alterations in brain functional connectivity patterns related to appetitive, relaxing, and stressful states. IMPLICATIONS: This study uses a data-driven approach to demonstrate that smokers and nonsmokers show differential patterns of functional connectivity during guided imagery related to personalized favorite-food, stress, and neutral-relaxing cues, in brain regions implicated in attention, reward-related, emotional, and motivational processes. For smokers, these differences in connectivity may impact appetite, stress, and relaxation, and may interfere with smoking cessation.
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