ArticleBrain, behavior, and immunity2016
Parental support buffers the association of depressive symptoms with cortisol and C-reactive protein during adolescence.
Article in Brain, behavior, and immunity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Link Between Positive and Negative Parenting Behaviors and Child Inflammation: A Systematic Review.Child psychiatry and human development · 2023Pooled it
- Lifelong Exercise as a Modulator of CD4European journal of clinical investigation · 2026Review
- Prevalence and risk factors for depression in somatic symptom disorder patients: a cross-sectional clinical study in China.BMC psychiatry · 2025Article
- An Extension to the stress-buffering model: Timing of support across the lifecourse.Brain, behavior, & immunity - health · 2024Article
- C-Reactive Protein and TGF-α Predict Psychological Distress at Two Years of Follow-Up in Healthy Adolescent Boys: The Fit Futures Study.Frontiers in psychology · 2022Article
- Social support and C-reactive protein in a Québec population cohort of children and adolescents.PloS one · 2022Article
- Associations Between Depressive Symptoms and Religiosity in Young Adults.Journal of religion and health · 2020Article
- Racial and ethnic differences in the associations between social integration, C-reactive protein and depressive symptoms.SSM - population health · 2020Article
- Sleep problems in adolescence are prospectively linked to later depressive symptoms via the cortisol awakening response.Development and psychopathology · 2020Article
- Persistent Low Positive Affect and Sleep Disturbance across Adolescence Moderate Link between Stress and Depressive Symptoms in Early Adulthood.Journal of abnormal child psychology · 2020Article
- The Interaction of Oxytocin and Social Support, Loneliness, and Cortisol Level in Major Depression.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2019Article
- Depressive symptoms and immune transcriptional profiles in late adolescents.Brain, behavior, and immunity · 2019Article
- Emotional Coregulation in Mexican-Origin Parent-Adolescent Dyads: Associations with Adolescent Mental Health.Journal of youth and adolescence · 2019Article
- Longitudinal associations between attachment quality in infancy, C-reactive protein in early childhood, and BMI in middle childhood: preliminary evidence from a CPS-referred sample.Attachment & human development · 2019Article
- Association of MAOA genetic variants and resilience with psychosocial stress: A longitudinal study of Syrian refugees.PloS one · 2019Article
- Cultural neurobiology and the family: Evidence from the daily lives of Latino adolescents.Development and psychopathology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Social experiences can affect the relationship between depression and physical health. The current study examined how social support from parents and friends may moderate the association of depressive symptoms with hypothalamic-pituitary-adrenal (HPA) axis activity and C-reactive protein among adolescents (N=316, Mage=16.40, SD=.74; 57% female) from diverse ethnic backgrounds (23.1% Asian, 29.1% European, 41.8% Latino, and 6.0% other backgrounds). Results indicated that parent support, but not friend support, moderated the link between depressive symptoms and both total daily cortisol output (a measure HPA activity) and C-reactive protein (a marker of inflammation). These patterns did not differ by ethnicity. Overall, the study highlights the continued, and perhaps accumulated, importance of parents during adolescence despite increasing needs for autonomy from and exploration outside of the family unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.