Evidence map›Paper›PMID 26994614›Full record

ArticleBriefings in bioinformatics2017

Tensor factorization toward precision medicine.

Yuan Luo, Fei Wang, Peter Szolovits

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
  10. CP Tensor Decomposition with Cannot-Link Intermode Constraints.Proceedings of the ... SIAM International Conference on Data Mining. SIAM International Conference on Data Mining · 2019
    Article
  11. Review
  12. Article
  13. Article
  14. Supervised Nonnegative Matrix Factorization to Predict ICU Mortality Risk.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2018
    Article
  15. Article
  16. Article
  17. High-fidelity phenotyping: richness and freedom from bias.Journal of the American Medical Informatics Association : JAMIA · 2018
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuan Luo
Fei Wang
Peter Szolovits

Funding

Informatics for Integrating Biology/ the Bedside (RMI)U54LM008748 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI KOHANE, ISAAC S. · 2004 to 2013
$39.0M
TrainingU54HG007963 · NHGRI · HARVARD MEDICAL SCHOOL · PI KOHANE, ISAAC S., MURPHY, SHAWN N · 2014 to 2018
$18.3M
NHGRI NIH HHS U54 HG007963NLM NIH HHS U54 LM008748
6 · The paper itself

Abstract

Precision medicine initiatives come amid the rapid growth in quantity and variety of biomedical data, which exceeds the capacity of matrix-oriented data representations and many current analysis algorithms. Tensor factorizations extend the matrix view to multiple modalities and support dimensionality reduction methods that identify latent groups of data for meaningful summarization of both features and instances. In this opinion article, we analyze the modest literature on applying tensor factorization to various biomedical fields including genotyping and phenotyping. Based on the cited work including work of our own, we suggest that tensor applications could serve as an effective tool to enable frequent updating of medical knowledge based on the continually growing scientific and clinical evidence. We encourage extensive experimental studies to tackle challenges including design choice of factorizations, integrating temporality and algorithm scalability.

Indexed as

Precision MedicineAlgorithmsGenotypeHumansbiomedical data miningmultiple data modalitiesprecision medicinetensor factorization

Identifiers

PMID26994614
PMCPMC6078180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.