Evidence map›Paper›PMID 26994526›Full record

ReviewSeminars in cell & developmental biology2016

Measuring time during early embryonic development.

Patrick L Ferree, Victoria E Deneke, Stefano Di Talia

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Clocks and Dominoes: Timing Mechanisms of Embryogenesis.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. The nuclear to cytoplasmic ratio directly regulates zygotic transcription inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Chemical waves in cell and developmental biology.The Journal of cell biology · 2018
    Review
  16. Mitotic waves in the early embryogenesis ofProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  17. Article
  18. A full lifespan model of vertebrate lens growth.Royal Society open science · 2017
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick L FerreeDepartment of Cell Biology, Duke University Medical Center, Durham NC, United States.
Victoria E DenekeDepartment of Cell Biology, Duke University Medical Center, Durham NC, United States.
Stefano Di TaliaDepartment of Cell Biology, Duke University Medical Center, Durham NC, United States. Electronic address: stefano.ditalia@duke.edu.

Funding

ORGANIZATION AND FUNCTIONS OF CELLULAR STRUCTUREST32GM007184 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 1985 to 2019
$18.2M
Time-keeping Mechanisms in Drosophila Embryonic DevelopmentR00HD074670 · NICHD · DUKE UNIVERSITY · PI DI TALIA, STEFANO · 2014 to 2016
$705k
NICHD NIH HHS R00 HD074670NIGMS NIH HHS T32 GM007184
6 · The paper itself

Abstract

In most metazoans, embryonic development is orchestrated by a precise series of cellular behaviors. Understanding how such events are regulated to achieve a stereotypical temporal progression is a fundamental problem in developmental biology. In this review, we argue that studying the regulation of the cell cycle in early embryonic development will reveal novel principles of how embryos accurately measure time. We will discuss the strategies that have emerged from studying early development of Drosophila embryos. By comparing the development of flies to that of other metazoans, we will highlight both conserved and alternative mechanisms to generate precision during embryonic development.

Indexed as

Embryonic DevelopmentAnimalsCell CycleGastrulationModels, BiologicalTime FactorsZygoteCell cycleEmbryonic developmentQuantitative biologySignalingTimingTranscription

Identifiers

PMID26994526
PMCPMC4903905

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.