Evidence map›Paper›PMID 26994487›Full record

ArticleInternational journal of surgery case reports2016

Male breast cancer, clinical presentation, diagnosis and treatment: Twenty years of experience in our Breast Unit.

A Sanguinetti, A Polistena, R Lucchini, M Monacelli, S Galasse, S Avenia, R Triola, W Bugiantella, R Cirocchi, F Rondelli and 1 more

Abstract read
In one paragraph

Article in International journal of surgery case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. A case report of male breast cancer treated with breast-conserving surgery.International journal of surgery case reports · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Unusual Male Breast Lesions.Journal of clinical imaging science · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A SanguinettiS. Maria University Hospital, Terni, Italy. Electronic address: alessandrosanguinetti@gmail.com.
A PolistenaUniversity of Perugia, Italy. Electronic address: apolis74@yahoo.it.
R LucchiniS. Maria University Hospital, Terni, Italy. Electronic address: robertalucchini@alice.it.
M MonacelliPerugia University Hospital, Italy. Electronic address: massimo.monacelli@gmail.com.
S GalasseS. Maria University Hospital, Terni, Italy. Electronic address: sergio.galasse@gmail.com.
S AveniaMedical School University of Perugia, Italy. Electronic address: stefano_avenia@libero.it.
R TriolaS. Maria University Hospital, Terni, Italy. Electronic address: atriolaroberta@gmail.com.
W BugiantellaUniversity of Perugia, Italy. Electronic address: walterbugiantella@alice.it.
R CirocchiUniversity of Perugia, Italy. Electronic address: roberto.cirocchi@unipg.it.
F RondelliUniversity of Perugia, Italy. Electronic address: rondellif@hotmail.com.
N AveniaUniversity of Perugia, Italy. Electronic address: nicolaavenia@libero.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe male breast cancer (MBC) is a rare and represents less than 1% of all malignancies in men and only 1% of all breast cancers incident. We illustrate the experience of our team about the clinico-pathological characteristics, treatment and prognostic factors of patients treated over a period of twenty years .

resultsForty-seven patients were collected 1995-2014 at the Breast Unit of the Hospital of Terni, Italy. The average age was 67 years and the median time to diagnosis from the onset of symptoms was 16 months. The main clinical complaint was sub areolar swelling in 36, 76% of cases. Most patients have come to our attention with advanced disease. The histology of about ninety percent of the tumors were invasive ductal carcinoma. Management consisted mainly of radical mastectomy; followed by adjuvant radiotherapy and hormonal therapy with or without chemotherapy. The median follow-up was 38 months. The evolution has been characterized by local recurrences; in eight cases (17% of all patients). Metastasis occurred in 15 cases (32% of all patients). The site of bone metastases was in eight cases; lung in four cases; liver in three cases; liver and skin in one case and pleura and skin in one case.

conclusionThe male breast cancer has many similarities to breast cancer in women, but there are distinct functions that need to be appreciated. Future research for a better understanding of the disease should provide a better account of genetic and epigenetic characteristics of these forms; but, above all, epidemiological and biological cohorts numerically more consistent.

Indexed as

ChemotherapyGeneticsHormonal treatmentMale breast cancerRadiotherapySurgeryTherapy

Identifiers

PMID26994487
PMCPMC4883054

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.