Evidence map›Paper›PMID 26994055›Full record

ArticleBMJ case reports2016

Diffuse large B-cell lymphoma of the adrenal gland: a rare cause of primary adrenal insufficiency.

Adriana de Sousa Lages, Margarida Bastos, Patrícia Oliveira, Francisco Carrilho

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Primary Adrenal Lymphoma: When B Symptoms Appear Hand in Hand with Adrenal Masses.European journal of case reports in internal medicine · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adriana de Sousa LagesDepartment of Endocrinology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Margarida BastosDepartment of Endocrinology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Patrícia OliveiraDepartment of Endocrinology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Francisco CarrilhoDepartment of Endocrinology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Hospitais da Universidade de Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although it is a rare entity, primary lymphoma of the adrenal gland should be considered in the differential diagnosis of bilateral nodular adrenal lesions, particularly when there is evidence of associated adrenal insufficiency. We describe the case of an 83-year-old woman admitted to the emergency department due to a month's history of asthenia, weight loss, anorexia and nausea. Abdominopelvic CT showed bilateral nodular lesions of adrenal glands and a stimulation test with tetracosactide was compatible with primary adrenal insufficiency. CT-guided biopsy of the left adrenal gland was performed, and histopathological results were consistent with diffuse large B-cell lymphoma. Positron emission tomography (18)F-fluorodeoxyglucose detected two intensely hypermetabolic lesions limited to both adrenal glands. Replacement therapy with hydrocortisone 15 mg/day and fludrocortisone 0.1 mg/day was promptly started and chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone was initiated after haematology-oncology consultation.

Indexed as

Addison DiseaseAdrenal Gland NeoplasmsAdrenal GlandsAdrenal InsufficiencyAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBiopsyDiagnosis, DifferentialFemaleFludrocortisoneHumansLymphoma, Large B-Cell, DiffusePositron-Emission TomographyFludrocortisone

Identifiers

PMID26994055
PMCPMC4800261
OpenAlexW2316872494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.