Evidence map›Paper›PMID 26993494›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Evaluation of a low-carbohydrate diet-based preparation protocol without fasting for cardiac PET/MR imaging.

Felix Nensa, E Tezgah, K Schweins, J Goebel, P Heusch, K Nassenstein, T Schlosser, T D Poeppel

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. [Hybrid PET/MRI for inflammatory cardiomyopathy].Radiologie (Heidelberg, Germany) · 2022
    Review
  5. Simultaneous measurements of myocardial glucose metabolism and extracellular volumes with hybrid PET/MRI using concurrent injections of Gd-DTPA and [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Review
  7. Article
  8. Review
  9. Characterization of a highly effective preparation for suppression of myocardial glucose utilization.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  10. Opening the door to noninvasive assessment of cardiac transplant rejection: It's all in the preparation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  11. The logic and challenges of imaging sarcoidosis with whole body FDG PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  12. Cardiac PET/MRI-an update.European journal of hybrid imaging · 2019
    Review
  13. Review
  14. Feasibility of FDG-PET in myocarditis: Comparison to CMR using integrated PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  15. Review
  16. Article
  17. PET/MR: Yet another Tesla?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Felix NensaDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany. felix.nensa@gmail.com.
E TezgahClinic for Cardiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
K SchweinsDepartment of Diet and Nutrition, University of Duisburg-Essen, Essen, Germany.
J GoebelDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
P HeuschDepartment of Diagnostic and Interventional Radiology, University Hospital Dusseldorf, University of Dusseldorf, Dūsseldorf, Germany.
K NassensteinDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
T SchlosserDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
T D PoeppelClinic for Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
University of Duisburg-Essen · DEDüsseldorf University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAssessment of increased glucose uptake in inflammatory or malignant myocardial disease using PET/MRI relies on uptake suppression in normal myocardium. We evaluated the efficacy of a ≥24 hours high-fat, low-carbohydrate, and protein-permitted diet (HFLCPP) in combination with unfractionated heparin for suppression of "physiologic" myocardial glucose uptake.

methodsPET/MRI was successfully performed in 89 patients. HFLCPP was started ≥24 hours prior to PET/MRI. All patients received i.v. injection of unfractionated heparin (50 IU·kg

resultsSuccess rate was 84%. Suppression was unsuccessful in 14 patients. No significant influence of gender (P = .40) or age (P = .21) was found. However, insufficient suppression was more common in patients younger than 45 years (20% vs 7%). PET/MR imaging completion rate was >97%.

conclusionA HFLCPP diet in combination with unfractionated heparin was successfully implemented for cardiac PET/MRI and resulted in a sufficient suppression of myocardial FDG uptake in 84% of patients.

Indexed as

AdultCardiac Imaging TechniquesDietary ProteinsDiet, Carbohydrate-RestrictedFastingFemaleFluorodeoxyglucose F18HeartHumansImage EnhancementMagnetic Resonance ImagingMaleMyocardiumPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsDietary ProteinsFluorodeoxyglucose F18Radiopharmaceuticalsfatty acid loadingfluorodeoxyglucose (FDG)high-fatlow-carbohydratePET/MRIprotein-permitted dietunfractionated heparin

Identifiers

PMID26993494
OpenAlexW2304253942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.