Evidence map›Paper›PMID 26992943›Full record

ArticleHaematologica2016

Genetic analysis of five children with essential thrombocytosis identified mutations in cancer-associated genes with roles in transcriptional regulation.

Nicole Kucine, Aaron D Viny, Raajit Rampal, Michael Berger, Nicholas Socci, Agnes Viale, James B Bussel, Ross L Levine, Franck Rapaport

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nicole KucineDepartment of Pediatrics, Division of Hematology/Oncology, Weill Cornell Medicine, New York, NY, USA nik9015@med.cornell.edu.
Aaron D VinyHuman Oncology and Pathogenesis Program; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Raajit RampalHuman Oncology and Pathogenesis Program; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Michael BergerCenter for Molecular Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Nicholas SocciCenter for Molecular Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Agnes VialeCenter for Molecular Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
James B BusselDepartment of Pediatrics, Division of Hematology/Oncology, Weill Cornell Medicine, New York, NY, USA.
Ross L LevineHuman Oncology and Pathogenesis Program; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Franck RapaportLeukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USMolecular Oncology (United States) · USCornell University · USWeill Cornell Medicine · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Institutional Career Development CoreKL2TR002385 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI YUAN-SHAN ZHU · 2017 to 2026
$13.3M
Genomic profiling and development of murine models of transformation of MPNsK08CA188529 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI RAMPAL, RAAJIT · 2014 to 2018
$891k
NCATS NIH HHS KL2 TR002385NCATS NIH HHS UL1 TR002384NCI NIH HHS K08 CA188529NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genes, NeoplasmMutationTranscription, GeneticAdolescentAdultChildChild, PreschoolDNA Mutational AnalysisFemaleHumansThrombocythemia, Essentialchronic myeloproliferative disorderscytogenetics and molecular geneticspediatric

Identifiers

PMID26992943
PMCPMC5013957
OpenAlexW2306940253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.