Evidence map›Paper›PMID 26992897›Full record

SynthesisObesity surgery2016

Effects of Bariatric Surgery on Mortality, Cardiovascular Events, and Cancer Outcomes in Obese Patients: Systematic Review and Meta-analysis.

Xu Zhou, Jiajie Yu, Ling Li, Viktoria Luise Gloy, Alain Nordmann, Maria Tiboni, Youping Li, Xin Sun

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06292936 (Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain), which is not on this map. Cited by 39 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06292936 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain

TypeinterventionalSponsorTemple UniversityRan2024 to 2028Enrolled200ConditionsObesity, Bariatric Surgery CandidateArmsAcceptance-Based Behavioral Intervention
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  11. Metabolic surgery versus usual care effects on mortality among patients with obesity and type 2 diabetes: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
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  17. Bariatric surgery reduces sleep apnea in obese patients with obstructive sleep apnea by increasing pharyngeal cross-sectional area during the early postoperative period.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xu ZhouChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Jiajie YuChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Ling LiChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Viktoria Luise GloyBasel Institute of Clinical Epidemiology & Biostatistics, University Hospital Basel, Hebelstrasse 10, Basel, Switzerland.
Alain NordmannBasel Institute of Clinical Epidemiology & Biostatistics, University Hospital Basel, Hebelstrasse 10, Basel, Switzerland.
Maria TiboniSaint Joseph's Hospital and McMaster University, Hamilton, ON, Canada.
Youping LiChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Xin SunChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China. sunx26@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term effects of bariatric surgery have yet to be established, and a number of important studies have recently emerged. This systematic review aimed to assess the effects of bariatric surgery on all-cause mortality, cardiovascular events, and cancer compared to non-surgical treatment.

methodsWe searched PubMed, EMBASE, and CENTRAL up to July 13, 2015, and included randomized controlled trials (RCTs) and non-randomized controlled studies comparing bariatric surgery versus non-surgical treatment and reporting data on the three defined outcomes at 1 year or longer. We analyzed RCTs and non-randomized controlled studies, respectively.

resultsEleven RCTs, 4 non-randomized controlled trials, and 17 cohort studies were included. The randomized evidence suggested substantial uncertainty regarding the effects on all-cause mortality (0/382 vs. 1/287; 7 studies), cancer (OR 0.77, 95 % CI 0.22 to 2.71; 4 studies), and cardiovascular events (no data). The pooled adjusted estimates from non-randomized studies suggested that, compared to the control, the surgical group had lower risk of all-cause mortality (OR 0.55, 95 % CI 0.46 to 0.65; 10 studies), cancer (OR 0.74, 95 % CI 0.65 to 0.85; 2 studies), and cardiovascular events (MI: OR 0.71, 95 % CI 0.54 to 0.94; stroke: OR 0.66, 95 % CI 0.49 to 0.89; and their composite: OR 0.67, 95 % CI 0.54 to 0.83; 1 study).

conclusionsIn conclusion, bariatric surgery could reduce all-cause mortality and probably reduce the risk of any type of cancer. The inference was, however, based on studies with limited methodological rigor. Uncertainty remains regarding the effects on cardiovascular events.

Indexed as

Bariatric SurgeryCardiovascular DiseasesHumansNeoplasmsObesityRandomized Controlled Trials as TopicRiskBariatric surgeryCancerCardiovascular eventsMortality

Identifiers

PMID26992897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.