Trial reportOncotarget2016
Development and validation of a prognostic nomogram based on the log odds of positive lymph nodes (LODDS) for breast cancer.
Trial report in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic models for breast cancer: a systematic review.BMC cancer · 2019Pooled it
- Utilising VISULYZE-Generated Nomograms and OcuLign Alignment Tools to Improve Keratorefractive Lenticule Extraction Outcomes.Journal of clinical medicine · 2026Article
- The deviation between achieved net corneal thinning and predicted lenticule thickness after keratorefractive lenticule extraction surgery.International ophthalmology · 2026Article
- Development and validation of a prognostic nomogram based on the clinical indicators for breast cancer.Gland surgery · 2026Article
- Prognostic value of metastatic lymph-node ratio and log-odds of positive nodes after neoadjuvant chemotherapy in breast cancer.World journal of surgical oncology · 2026Article
- Log odds of positive lymph nodes as a prognostic marker in resectable triple negative breast cancer.Scientific reports · 2025Article
- Evaluation of three lymph node staging systems for prognostic prediction in gastric cancer: A systematic review and meta-analysis.World journal of gastrointestinal oncology · 2025Article
- Log odds of positive lymph nodes (LODDS)-based novel nomogram for survival estimation in patients with invasive micropapillary carcinoma of the breast.BMC medical research methodology · 2024Article
- Article
- A Nomogram Based on SEER Database for Predicting Prognosis in Patients with Mucinous Ovarian Cancer: A Real-World Study.International journal of women's health · 2022Article
- Developing and validating a prognostic nomogram for ovarian clear cell carcinoma patients: A retrospective comparison of lymph node staging schemes with competing risk analysis.Frontiers in oncology · 2022Article
- Development and validation of multiparametric MRI-based nomogram for predicting occult metastasis risk in early tongue squamous cell carcinoma.BMC cancer · 2021Article
- The role of different lymph node staging systems in predicting prognosis and determining indications for postmastectomy radiotherapy in patients with T1-T2pN1 breast carcinoma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Article
- Development of a nomogram to predict prognosis in ovarian cancer: a SEER-based study.Translational cancer research · 2020Article
- Article
- Nomograms for predicting overall and cancer-specific survival in patients with papillary renal cell carcinoma: a population-based study using SEER database.Translational andrology and urology · 2020Article
- Application of nomogram containing log odds of metastatic lymph node in gallbladder cancer patients.Annals of translational medicine · 2020Article
- Modified lymph node ratio improves the prognostic predictive ability for breast cancer patients compared with other lymph node staging systems.Breast (Edinburgh, Scotland) · 2020Article
- Comparison of different lymph node staging schemes in prostate cancer patients with lymph node metastasis.International urology and nephrology · 2020Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the prognostic effect of log odds of positive lymph nodes (LODDS) and develop a nomogram for survival prediction in breast cancer patients at the time of surgery.
resultsLODDS was an independent risk factor for cancer-related death in breast cancer (hazard ratio: 1.582, 95%CI: 1.190-2.104). Menopausal status, tumor size, pathological lymph node staging, estrogen receptor status and human epidermal growth factor receptor-2 status were also included in the nomogram. The calibration plots indicated optimal agreement between the nomogram prediction and actual observation. Discrimination of nomogram was superior to the seventh edition TNM staging system [C-index: 0.745 vs. 0.721 (p = 0.03) in training cohort; 0.796 vs. 0.726 (p < 0.01) in validation cohort].
methodsWe retrospectively evaluated 2023 breast cancer patients from Jan 2002 to Dec 2008 at our center. The cohort was randomly divided into training cohort and validation cohort. Univariate and multivariate analyses were performed to identify prognostic factors, and nomogram was established using Cox regression model in training cohort. External validation of the nomogram was performed in the validation cohort.
conclusionsThe LODDS is an independent prognostic indicator in breast cancer and the novel nomogram can provide individual prediction of cancer-specific survival and help prognostic assessment for breast cancer patients.
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