Trial reportObesity (Silver Spring, Md.)2016
The impact of continued intervention on weight: Five-year results from the weight loss maintenance trial.
Trial report in Obesity (Silver Spring, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Dietary Strategies for Weight Loss Maintenance.Nutrients · 2019Pooled it
- Trial
- Fetuin-B, a potential link of liver-adipose tissue cross talk during diet-induced weight loss-weight maintenance.Nutrition & diabetes · 2021Trial
- Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study.Obesity (Silver Spring, Md.) · 2020Trial
- Trial
- Weight maintenance after discontinuation of GLP-1 therapies.EClinicalMedicine · 2026Review
- Anti-obesity treatment preferences of healthcare providers and people living with obesity: A survey-based study.Clinical obesity · 2025Article
- Does intervention sequence impact self-regulatory and behavioral outcomes in an adaptive trial among adults with prediabetes?Health psychology and behavioral medicine · 2024Article
- CRISPR/Cas9 Technology: A Novel Approach to Obesity Research.Current pharmaceutical design · 2024Review
- Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment.Current diabetes reports · 2023Review
- Outcomes of bariatric surgery in elderly patients: a registry-based cohort study with 3-year follow-up.International journal of obesity (2005) · 2022Article
- Two-year weight trajectories following completion of a behavioral weight loss maintenance intervention.Obesity science & practice · 2021Article
- The limits and challenges of antiobesity pharmacotherapy.Expert opinion on pharmacotherapy · 2020Review
- Four main barriers to weight loss maintenance? A quantitative analysis of difficulties experienced by obese patients after successful weight reduction.European journal of clinical nutrition · 2020Article
- The Effect of Bariatric Surgery on Weight Loss and Metabolic Changes in Adults with Obesity.International journal of environmental research and public health · 2020Article
- What Happens to Adults, From Different Socio-Economic Backgrounds, Who Join a Community Weight Management Programme? Long-Term Outcomes up to Nine Years After First Joining.Journal of primary care & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
objectiveIn the Weight Loss Maintenance (WLM) Trial, a personal contact (PC) intervention sustained greater weight loss relative to a self-directed (SD) group over 30 months. This study investigated the effects of continued intervention over an additional 30 months and overall weight change across the entire WLM Trial.
methodsWLM had 3 phases. Phase 1 was a 6-month weight loss program. In Phase 2, those who lost ≥4 kg were randomized to a 30-month maintenance trial. In Phase 3, PC participants (n = 196, three sites) were re-randomized to no further intervention (PC-Control) or continued intervention (PC-Active) for 30 more months; 218 SD participants were also followed.
resultsDuring Phase 3, weight increased 1.0 kg in PC-Active and 0.5 kg in PC-Control (mean difference 0.6 kg; 95% CI:-1.4 to 2.7; P = 0.54). Mean weight change over the entire study was -3.2 kg in those originally assigned to PC (PC-Combined) and -1.6 kg in SD (mean difference -1.6 kg; 95% CI:-3.0 to -0.1; P = 0.04).
conclusionsAfter 30 months of the PC maintenance intervention, continuation for another 30 months provided no additional benefit. However, across the entire study, weight loss was slightly greater in those originally assigned to PC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.