Evidence map›Paper›PMID 26991333›Full record

ArticleAngewandte Chemie (International ed. in English)2016

H2 -Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration.

Óscar Gutiérrez-Sanz, Paolo Natale, Ileana Márquez, Marta C Marques, Sonia Zacarias, Marcos Pita, Inês A C Pereira, Iván López-Montero, Antonio L De Lacey, Marisela Vélez

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 53 citations in OpenAlex.

  1. Electroenzymatic COAngewandte Chemie (International ed. in English) · 2026
    Review
  2. Article
  3. Article
  4. Rotation of the c-Ring Promotes the Curvature Sorting of Monomeric ATP Synthases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Nonequilibrium fluctuations of lipid membranes by the rotating motor protein FProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  11. Article
  12. Supramolecular electrode assemblies for bioelectrochemistry.Chemical communications (Cambridge, England) · 2017
    Review
  13. H2 -Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration.Angewandte Chemie (International ed. in English) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Óscar Gutiérrez-SanzInstituto de Catálisis y Petroleoquímica, CSIC, c/ Marie Curie 2, 28049, Madrid, Spain.
Paolo NataleUniversidad Complutense de Madrid, Avda. Complutense s/n, 28040, Madrid, Spain.
Ileana MárquezInstituto de Catálisis y Petroleoquímica, CSIC, c/ Marie Curie 2, 28049, Madrid, Spain.
Marta C MarquesInstituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Apartado 127, 2781-901, Oeiras, Portugal.
Sonia ZacariasInstituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Apartado 127, 2781-901, Oeiras, Portugal.
Marcos PitaInstituto de Catálisis y Petroleoquímica, CSIC, c/ Marie Curie 2, 28049, Madrid, Spain.
Inês A C PereiraInstituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Apartado 127, 2781-901, Oeiras, Portugal.
Iván López-MonteroUniversidad Complutense de Madrid, Avda. Complutense s/n, 28040, Madrid, Spain. ivanlopez@quim.ucm.es.
Antonio L De LaceyInstituto de Catálisis y Petroleoquímica, CSIC, c/ Marie Curie 2, 28049, Madrid, Spain. alopez@icp.csic.es.
Marisela VélezInstituto de Catálisis y Petroleoquímica, CSIC, c/ Marie Curie 2, 28049, Madrid, Spain. marisela.velez@icp.csic.es.
Instituto de Catálisis y Petroleoquímica · ESUniversidade Nova de Lisboa · PTInstituto de Biologia Experimental e Tecnológica · PTResearch Institute Hospital 12 de Octubre · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ATP, the molecule used by living organisms to supply energy to many different metabolic processes, is synthesized mostly by the ATPase synthase using a proton or sodium gradient generated across a lipid membrane. We present evidence that a modified electrode surface integrating a NiFeSe hydrogenase and a F1 F0 -ATPase in a lipid membrane can couple the electrochemical oxidation of H2 to the synthesis of ATP. This electrode-assisted conversion of H2 gas into ATP could serve to generate this biochemical fuel locally when required in biomedical devices or enzymatic synthesis of valuable products.

Indexed as

Adenosine TriphosphateElectrochemical TechniquesElectrodesHydrogenHydrogenaseLipid BilayersMicroscopy, Atomic ForceMitochondrial Proton-Translocating ATPasesOxidation-ReductionQuartz Crystal Microbalance TechniquesAdenosine TriphosphateF1F0-ATP synthaseHydrogenHydrogenaseLipid BilayersMitochondrial Proton-Translocating ATPasesnickel-iron-selenium hydrogenasebioelectrochemistrybiophysicsimmobilizationmembrane proteinsproton transport

Identifiers

PMID26991333
PMCPMC5132028
OpenAlexW2299305482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.