ArticleHuman brain mapping2016
Multidimensional representation of odors in the human olfactory cortex.
Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 55 citations in OpenAlex.
- Separable and integrated pleasantness coding for appetitive and aversive odors across olfactory and ventral prefrontal cortices.Nature communications · 2026Article
- Behavioral Relevance of Early Neural Coding of Low-Level Odor Features in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Substitution of human olfaction by the trigeminal system.Science advances · 2025Article
- Collaborative rule learning promotes interbrain information alignment.PLoS biology · 2025Article
- The topology and geometry of neural representations.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Decomposition of an odorant in olfactory perception and neural representation.Nature human behaviour · 2024Article
- Semantic context-dependent neural representations of odors in the human piriform cortex revealed by 7T MRI.Human brain mapping · 2024Article
- Leveraging multi-echo EPI to enhance BOLD sensitivity in task-based olfactory fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Representational maps in the brain: concepts, approaches, and applications.Frontiers in cellular neuroscience · 2024Review
- High-precision mapping reveals the structure of odor coding in the human brain.Nature neuroscience · 2023Article
- Physicochemical features partially explain olfactory crossmodal correspondences.Scientific reports · 2023Article
- Odor discrimination is immune to the effects of verbal labels.Scientific reports · 2023Article
- Odor Pleasantness Modulates Functional Connectivity in the Olfactory Hedonic Processing Network.Brain sciences · 2022Article
- Spatiotemporal dynamics of odor representations in the human brain revealed by EEG decoding.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Validation of Olfactory Network Based on Brain Structural Connectivity and Its Association With Olfactory Test Scores.Frontiers in systems neuroscience · 2021Article
- Clinical Implications of Psychophysical Olfactory Testing: Assessment, Diagnosis, and Treatment Outcome.Frontiers in neuroscience · 2021Review
- Assessment of direct knowledge of the human olfactory system.Experimental neurology · 2020Review
- Article
- Specific intranasal and central trigeminal electrophysiological responses in Parkinson's disease.Journal of neurology · 2019Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What is known as an odor object is an integrated representation constructed from physical features, and perceptual attributes mainly mediated by the olfactory and trigeminal systems. The aim of the present study was to comprehend how this multidimensional representation is organized, by deciphering how similarities in the physical, olfactory and trigeminal perceptual spaces of odors are represented in the human brain. To achieve this aim, we combined psychophysics, functional MRI and multivariate representational similarity analysis. Participants were asked to smell odors diffused by an fMRI-compatible olfactometer and to rate each smell along olfactory dimensions (pleasantness, intensity, familiarity and edibility) and trigeminal dimensions (irritation, coolness, warmth and pain). An event-related design was implemented, presenting different odorants. Results revealed that (i) pairwise odorant similarities in anterior piriform cortex (PC) activity correlated with pairwise odorant similarities in chemical properties (P < 0.005), (ii) similarities in posterior PC activity correlated with similarities in olfactory perceptual properties (P <0.01), and (iii) similarities in amygdala activity correlated with similarities in trigeminal perceptual properties (P < 0.01). These findings provide new evidence that extraction of physical, olfactory and trigeminal features is based on specific fine processing of similarities between odorous stimuli in a distributed manner in the olfactory system. Hum Brain Mapp 37:2161-2172, 2016. © 2016 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.