ArticleMolecular cell2016
Rewiring Cas9 to Target New PAM Sequences.
Article in Molecular cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria.Metabolic engineering · 2023Article
- Genome editing with type II-C CRISPR-Cas9 systems from Neisseria meningitidis in rice.Plant biotechnology journal · 2022Article
- Engineering a PAM-flexible SpdCas9 variant as a universal gene repressor.Nature communications · 2021Article
- Recent advances in CRISPR/Cas9 mediated genome editing in Bacillus subtilis.World journal of microbiology & biotechnology · 2018Review
- Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape.Journal of industrial microbiology & biotechnology · 2018Review
- Protein Engineering Strategies to Expand CRISPR-Cas9 Applications.International journal of genomics · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Papers by Anders et al. (2016) and Hirano et al. (2016b), published in this issue of Molecular Cell, show that SpCas9 uses an induced fit mechanism to recognize altered protospacer adjacent motif (PAM) sequences.
Indexed as
Identifiers
26990984What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.