Evidence map›Paper›PMID 26990618›Full record

ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2016

3D Super-Resolution Motion-Corrected MRI: Validation of Fetal Posterior Fossa Measurements.

Danielle B Pier, Ali Gholipour, Onur Afacan, Clemente Velasco-Annis, Sean Clancy, Kush Kapur, Judy A Estroff, Simon K Warfield

Abstract readValidation Study
In one paragraph

Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Fetal Neuroimaging Updates.Magnetic resonance imaging clinics of North America · 2021
    Review
  12. Article
  13. Review
  14. Review
  15. Brain growth in fetuses with congenital diaphragmatic hernia.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Danielle B PierDepartment of Neurology, Boston Children's Hospital, Boston, MA.
Ali GholipourDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Onur AfacanDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Clemente Velasco-AnnisDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Sean ClancyDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Kush KapurDepartment of Neurology, Boston Children's Hospital, Boston, MA.
Judy A EstroffDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Simon K WarfieldDepartment of Radiology, Boston Children's Hospital, Boston, MA.
Boston Children's Hospital · USBoston Children's Museum · USHarvard University · US

Funding

Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI KUNKEL, LOUIS M · 2016 to 2020
$5.2M
CH/BIDMC/Harvard Medical School Neurology Resident Research Education Program Competing RenewalR25NS070682 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI PODURI, ANNAPURNA, SAPER, CLIFFORD B · 2010 to 2023
$4.5M
Motion-robust super-resolution diffusion weighted MRI of early brain developmentR01EB018988 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI GHOLIPOUR-BABOLI, ALI · 2014 to 2017
$1.6M
Improved Quantitative Assessment of the Fetal Brain from 3D Volumetric MRIR01EB013248 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2012 to 2015
$1.5M
NIBIB NIH HHS R01 EB013248NIBIB NIH HHS R01 EB018988NICHD NIH HHS U54 HD090255NINDS NIH HHS R25 NS070682
6 · The paper itself

Abstract

purposeCurrent diagnosis of fetal posterior fossa anomalies by sonography and conventional MRI is limited by fetal position, motion, and by two-dimensional (2D), rather than three-dimensional (3D), representation. In this study, we aimed to validate the use of a novel magnetic resonance imaging (MRI) technique, 3D super-resolution motion-corrected MRI, to image the fetal posterior fossa.

methodsFrom a database of pregnant women who received fetal MRIs at our institution, images of 49 normal fetal brains were reconstructed. Six measurements of the cerebellum, vermis, and pons were obtained for all cases on 2D conventional and 3D reconstructed MRI, and the agreement between the two methods was determined using concordance correlation coefficients. Concordance of axial and coronal measurements of the transcerebellar diameter was also assessed within each method.

resultsBetween the two methods, the concordance of measurements was high for all six structures (P < .001), and was highest for larger structures such as the transcerebellar diameter. Within each method, agreement of axial and coronal measurements of the transcerebellar diameter was superior in 3D reconstructed MRI compared to 2D conventional MRI (P < .001).

conclusionsThis comparison study validates the use of 3D super-resolution motion-corrected MRI for imaging the fetal posterior fossa, as this technique results in linear measurements that have high concordance with 2D conventional MRI measurements. Lengths of the transcerebellar diameter measured within a 3D reconstruction are more concordant between imaging planes, as they correct for fetal motion and orthogonal slice acquisition. This technique will facilitate further study of fetal abnormalities of the posterior fossa.

Indexed as

Cranial Fossa, PosteriorFemaleFetusHealthy VolunteersHumansImaging, Three-DimensionalMagnetic Resonance ImagingNeuroimagingPregnancyPrenatal Diagnosis3D reconstructioncerebellumFetal MRIposterior fossasuper resolutionvermis

Identifiers

PMID26990618
PMCPMC4983257
OpenAlexW2297631882

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.