Evidence map›Paper›PMID 26990413›Full record

ArticleJournal of the American Chemical Society2016

A General Method for Aminoquinoline-Directed, Copper-Catalyzed sp(2) C-H Bond Amination.

James Roane, Olafs Daugulis

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  7. The Journal of organic chemistry · 2019
    Article
  8. Article
  9. Article
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  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Intermolecular Aryl C-H Amination through Sequential Iron and Copper Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James RoaneDepartment of Chemistry, University of Houston , Houston, Texas 77204-5003, United States.
Olafs DaugulisDepartment of Chemistry, University of Houston , Houston, Texas 77204-5003, United States.

Funding

New Methods for Direct Carbon-Hydrogen Bond FunctionalizationR01GM077635 · NIGMS · UNIVERSITY OF HOUSTON · PI DAUGULIS, OLAFS · 2007 to 2020
$3.6M
NIGMS NIH HHS R01 GM077635NIGMS NIH HHS R01GM077635
6 · The paper itself

Abstract

An operationally simple and general method for copper-catalyzed, aminoquinoline-assisted amination of β-C(sp(2))-H bonds of benzoic acid derivatives is reported. The reaction employs Cu(OAc)2 or (CuOH)2CO3 catalysts, an amine coupling partner, and oxygen from air as a terminal oxidant. Exceptionally high generality with respect to amine coupling partners is observed. Specifically, primary and secondary aliphatic and aromatic amines, heterocycles, such as indoles, pyrazole, and carbazole, sulfonamides, as well as electron-deficient aromatic and heteroaromatic amines are competent coupling components.

Indexed as

AminationAminoquinolinesBenzoatesCatalysisCombinatorial Chemistry TechniquesCopperMolecular StructureAminoquinolinesBenzoatesCopper

Identifiers

PMID26990413
PMCPMC4829344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.