Evidence map›Paper›PMID 26990361›Full record

ArticleJournal of biophotonics2016

Repeated transcranial low-level laser therapy for traumatic brain injury in mice: biphasic dose response and long-term treatment outcome.

Weijun Xuan, Liyi Huang, Michael R Hamblin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Weijun XuanDept of Otorhinolaryngology, Head and Neck Surgery, Ruikang Clinical Medical College, Guangxi University of Chinese Medicine, Nanning, China.
Liyi HuangWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Harvard–MIT Division of Health Sciences and Technology · USHarvard University · USMassachusetts General Hospital · US

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
NIAID NIH HHS R01 AI050875
6 · The paper itself

Abstract

We previously showed that near-infrared laser photobiomodulation (PBM) (810 nm, CW, 18 J/cm

Indexed as

Low-Level Light TherapyAnimalsBrainBrain Injuries, TraumaticDose-Response Relationship, RadiationGlial Fibrillary Acidic ProteinMiceTreatment OutcomeGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mousebiphasic dose responsecontrolled cortical impact mouse modelglial fibrillary acidic proteinLLLTMorris water mazephotobiomodulationreactive gliosisTraumatic brain injury

Identifiers

PMID26990361
PMCPMC5025344
OpenAlexW2298986670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.