Evidence map›Paper›PMID 26990294›Full record

ArticleThe British journal of dermatology2016

Primary care-based screening for cardiovascular risk factors in patients with psoriasis.

M K Rutter, K Kane, M Lunt, L Cordingley, A Littlewood, H S Young, C A Chew-Graham, R Hilton, D P M Symmons, C E M Griffiths

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in The British journal of dermatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
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  10. Review
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  14. Review
  15. Article
  16. Cardiometabolic Comorbidities in Psoriasis and Psoriatic Arthritis.International journal of molecular sciences · 2017
    Review
  17. Article
  18. Cardiometabolic Disorders in Psoriatic Disease.Current rheumatology reports · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

M K RutterThe Endocrinology and Diabetes Research Group, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
K KaneCentre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
M LuntArthritis Research U.K. Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
L CordingleyCentre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
A LittlewoodCentre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
H S YoungCentre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
C A Chew-GrahamResearch Institute, Primary Care and Health Sciences, Keele University, Keele, U.K.
R HiltonBridgewater Community Healthcare NHS Trust, Wigan, U.K.
D P M SymmonsArthritis Research U.K. Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
C E M GriffithsCentre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, U.K.
Manchester Academic Health Science Centre · GBBridgewater Community Healthcare NHS Foundation Trust · GBNIHR Manchester Biomedical Research Centre · GBNorth Staffordshire Combined Healthcare NHS Trust · GBVersus Arthritis · GB

Funding

Department of Health RP-PG-0608-10163Department of Health WMCLAHRC-2014-1
6 · The paper itself

Abstract

backgroundStudies assessing cardiovascular disease (CVD) risk factors in patients with psoriasis have been limited by selection bias, inappropriate controls or a reliance on data collected for clinical reasons.

objectivesTo investigate whether screening for CVD risk factors in patients with psoriasis in primary care augments the known prevalence of CVD risk factors in a cross-sectional study.

methodsPatients listed as having psoriasis in primary care were recruited, screened and risk assessed by QRISK2.

resultsIn total, 287 patients attended (mean age 53 years, 57% women, 94% white British, 22% severe disease, 33% self-reported psoriatic arthritis). The proportion with known and screen-detected (previously unknown) risk factors was as follows: hypertension 35% known and 13% screen-detected; hypercholesterolaemia 32% and 37%; diabetes 6·6% and 3·1% and chronic kidney disease 1·1% and 4·5%. At least one screen-detected risk factor was found in 48% and two or more risk factors were found in 21% of patients. One in three patients (37%) not previously known to be at high risk were found to have a high (> 10%) 10-year CVD risk. Among the participants receiving treatment for known CVD risk factors, nearly half had suboptimal levels for blood pressure (46%) and cholesterol (46%).

conclusionsCardiovascular risk factor screening of primary care-based adults with psoriasis identified a high proportion of patients (i) at high CVD risk, (ii) with screen-detected risk factors and (iii) with suboptimally managed known risk factors. These findings need to be considered alongside reports that detected limited responses of clinicians to identified risk factors before universal CVD screening can be recommended.

Indexed as

Arthritis, PsoriaticCardiovascular DiseasesCross-Sectional StudiesDiabetes ComplicationsEnglandFemaleHumansHypercholesterolemiaHypertensionMaleMiddle AgedPrevalencePsoriasisRenal Insufficiency, ChronicRisk FactorsSelf Report

Identifiers

PMID26990294
PMCPMC5113692
OpenAlexW2298671661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.