ArticleDepression and anxiety2017
The Role of Response Inhibition in Medicated and Unmedicated Obsessive-Compulsive Disorder Patients: Evidence from the Stop-Signal Task.
Article in Depression and anxiety, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Modulation of motor inhibition by subthalamic stimulation in obsessive-compulsive disorder.Translational psychiatry · 2016Trial
- A Multi-Symptom Circuit Architecture of Obsessive-Compulsive Disorder.medRxiv : the preprint server for health sciences · 2025Article
- The rollercoaster of obsessive-compulsive disorder: How chronotype and time of day affect behavioral inhibition in adults with OCD.Journal of mood and anxiety disorders · 2025Article
- Association Between Coffee Intake and Common Mental Disorders: Insights From Genetic Analysis.CNS neuroscience & therapeutics · 2025Article
- The Effect of Symptom-Provocation on Inhibitory Control in Obsessive-Compulsive Disorder Patients Is Contingent upon Chronotype and Time of Day.Journal of clinical medicine · 2023Article
- Response Inhibition in Youth Undergoing Intensive Treatment for Obsessive Compulsive Disorder.Journal of obsessive-compulsive and related disorders · 2023Article
- An Integrative Model for Understanding Obsessive-Compulsive Disorder: Merging Cognitive Behavioral Theory with Insights from Clinical Neuroscience.Journal of clinical medicine · 2022Article
- Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive-Compulsive Disorder.Frontiers in human neuroscience · 2022Review
- Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder.Molecular psychiatry · 2021Review
- Stopping a Response When You Really Care about the Action: Considerations from a Clinical Perspective.Brain sciences · 2021Review
- Executive Functioning and Clinical Variables in Patients with Obsessive-Compulsive Disorder.Brain sciences · 2021Article
- Neurocognitive Endophenotypes of OCD.Current topics in behavioral neurosciences · 2021Article
- Exploring response inhibition and error monitoring in obsessive-compulsive disorder.Journal of psychiatric research · 2020Article
- Temporal cascade of frontal, motor and muscle processes underlying human action-stopping.eLife · 2020Article
- Evidence for trial-by-trial dynamic adjustment of task control in unmedicated adults with OCD.Behaviour research and therapy · 2020Article
- Inhibition-related differences between tic-free and tic-related obsessive-compulsive disorder: evidence from the N2 and P3.Experimental brain research · 2019Article
- Response inhibition and error-monitoring processes in individuals with obsessive-compulsive disorder.Journal of obsessive-compulsive and related disorders · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundNumerous studies have investigated response inhibition (RI) in obsessive-compulsive disorder (OCD), with many reporting that OCD patients demonstrate deficits in RI as compared to controls. However, reported effect sizes tend to be modest and results have been inconsistent, with some studies finding intact RI in OCD. To date, no study has examined the effect of medications on RI in OCD patients.
methodsWe analyzed results from a stop-signal task to probe RI in 65 OCD patients (32 of whom were medicated) and 58 healthy controls (HCs).
resultsThere was no statistically significant difference in stop-signal reaction time between the OCD group and the HC group, or between the medicated and unmedicated OCD patients. However, variability was significantly greater in the medicated OCD group compared to the unmedicated group.
conclusionsThese results indicate that some samples of OCD patients do not have deficits in RI, making it unlikely that deficient RI underlies repetitive behaviors in all OCD patients. Future research is needed to fully elucidate the impact of medication use on stop-signal performance. Implications for future research on the cognitive processes underlying repetitive thoughts and behaviors are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.