Evidence map›Paper›PMID 26989915›Full record

ReviewJournal of pediatric hematology/oncology2016

Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities.

John Glod, Gilbert J Rahme, Harpreet Kaur, Eric H Raabe, Eugene I Hwang, Mark A Israel

Abstract readReview
In one paragraph

Review in Journal of pediatric hematology/oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  15. Molecular Basis of Pediatric Brain Tumors.Neuromolecular medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John GlodDepartments of †Genetics **Pediatrics ‡Geisel School of Medicine at Dartmouth, Norris Cotton Cancer Center, Hanover, NH *Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda §Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center ∥Division of Pediatric Oncology, Johns Hopkins School of Medicine, Bloomberg Children's Hospital, Baltimore, MD ¶The Brain Tumor Institute #Division of Hematology-Oncology, Children's National Medical Center, Washington, DC.
Gilbert J Rahme
Harpreet Kaur
Eric H Raabe
Eugene I Hwang
Mark A Israel

Funding

Pediatric Oncology Branch Clinical Care and EducationZIEBC011516 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GLOD, JOHN · 2013 to 2025
$69.1M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Great progress has been made in many areas of pediatric oncology. However, tumors of the central nervous system (CNS) remain a significant challenge. A recent explosion of data has led to an opportunity to understand better the molecular basis of these diseases and is already providing a foundation for the pursuit of rationally chosen therapeutics targeting relevant molecular pathways. The molecular biology of pediatric brain tumors is shifting from a singular focus on basic scientific discovery to a platform upon which insights are being translated into therapies.

Indexed as

Central Nervous System NeoplasmsBrain NeoplasmsChildGliomaHumansMedulloblastomaMolecular Biology

Identifiers

PMID26989915
PMCPMC5003110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.